Barrett's Oesophagus : Esomeprazole Magnesium Vs. Omeprazole
Definition
Barrett's oesophagus (American English: esophagus) (sometimes called Barrett's syndrome, CELLO, columnar epithelium lined lower oesophagus) refers to an abnormal change (metaplasia) in the cells of the inferior portion of the oesophagus. A positive diagnosis generally requires observing specific macroscopic and microscopic changes. The normal squamous epithelium lining of the oesophagus is replaced by metaplastic columnar epithelium. Columnar epithelium refers to a cell type that is typically found in more distal parts of the gastrointestinal system. The medical significance of Barrett’s oesophagus is its strong association with oesophageal adenocarcinoma, a particularly lethal cancer.
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