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Nicotine Dependence : Varenicline Tartrate Vs. Nicotine

Definition

Nicotine is an alkaloid found in the nightshade family of plants (Solanaceae) that constitutes approximately 0.6–3.0% of dry weight of tobacco, with biosynthesis taking place in the roots and accumulation occurring in the leaves. It functions as an antiherbivore chemical with particular specificity to insects; therefore nicotine was widely used as an insecticide in the past, and currently nicotine analogs such as imidacloprid continue to be widely used. Nicotine is also found in several other members of the Solanaceae family, with small amounts being present in species such as the Eggplant and Tomato.

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