Thalassemia (also spelled thalassaemia) is an inherited autosomal recessive blood disease. In thalassemia, the genetic defect which could be either mutations or deletion results in reduced rate of synthesis or no synthesis of one of the globin chains that make up hemoglobin. Reduced synthesis or no synthesis of one of the globin chains can cause the formation of abnormal hemoglobin molecules, thus causing anemia, the characteristic presenting symptom of the thalassemias.Read more on Wikipedia
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