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Toxocariasis : Albendazole Vs. Thiabendazole

Definition

Toxocariasis (also named toxocaral disease, toxocarose, covert toxocariasis, visceral lava migrans (VLM) or ocular larva migrans (OLM)) is a zoonotic, helminthic infection of humans caused by the dog roundworm (Toxocara canis) or cat roundworm (Toxocara cati). Humans normally become infected by ingestion of embryonated eggs (each containing a fully developed larva, L2) from contaminated sources. Humans are 'accidental' or paratenic hosts, which inhibits L2 larvae maturation within humans. There are three main syndromes: visceral larva migrans (VLM), which encompasses diseases associated with major organs; covert toxocariasis, which is a milder version of VLM; and ocular larva migrans (OLM), in which pathological effects on the host are restricted to the eye and the optic nerve.

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