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Hydromorphone is a more common synonym for dihydromorphinone, commonly a hydrochloride (brand names Palladone, Dilaudid, and numerous others). Not to be confused with dihydromorphine, which is a different derivative of the morphine family. It is a very potent centrally acting analgesic drug of the opioid class. It is a derivative of morphine; to be specific, it is a hydrogenated ketone thereof. Comparatively, hydromorphone is to morphine as hydrocodone is to codeine—that is, a semi-synthetic drug. In medical terms, it is an opioid analgesic and, in legal terms, a narcotic. Hydromorphone is commonly used in the hospital setting, mostly intravenously (IV) because its bioavailability is very low orally, rectally, and intranasally. Sublingual administration (under the tongue) is usually superior to swallowing for bioavailability and effects; however, hydromorphone is bitter and hydrophilic like most opiates, not lipophilic, so it is absorbed poorly and slowly through mouth membranes.

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* Extracted from FDA Adverse Event Reports for all drugs with the same active ingredients.

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Druginformer Identified Side Effects: None

Posted By Anonymous in drugs.com on June 4, 2012 @ 12:00 am

Palladone is a very effective medicine for pain control. My wife has MS and severe back pain from early arthritis, and one pill a day controls it just fine. Without it she is in constant pain and can ...

Druginformer Identified Side Effects: None

Posted By thepirate25@yahoo.com in fdb.rxlist.com on April 1, 2010 @ 12:00 am

Was on Pallodone worked wonders on me is it still out there or still banned??? Is it a form of Diludid??? I have RSD and i am on Methadone and now on Oxycontin would love to be able to be back on Pall...

Druginformer Identified Side Effects: None

Posted By ZABORAV in prescriptiondrug-info.com on October 1, 2011 @ 12:00 am

Verwon, typo? Should that not be 'acute' rather than 'chronic'? The m/r version, OxyContin, is far more likely to be given to the chronic patient, whereas acute pain will normally be dealt with using ...

Druginformer Identified Side Effects: None

Posted By Robert Marcello in prescriptiondrug-info.com on September 19, 2011 @ 12:00 am

What Additives Is In Oxycodone Ir 5 Mg What does the "IR" stand for located behind the word Oxycodone and in front of the dosage amount, i.e., 5 mg. When I look up he generic Oxycodone I see that i...

Druginformer Identified Side Effects: Muscle spasms

Posted By poppypanda in mdjunction.com on August 27, 2011 @ 12:00 am

... , all being treated by medication , palladone, lycria, omeprazole and iron tablets and have had sacral facet joint injection 3 weeks ago.lately i am having the most awful muscle cramps in my legs i h...

Druginformer Identified Side Effects: None

Posted By Cats Meow in drugs.com on April 21, 2010 @ 12:00 am

GC/MS is the most reliable test. You must not live in the USA, Palladone was pulled from the market here in 2005 because when it was mixed with alcohol people were ODing and dropping like flies. A n...

Druginformer Identified Side Effects: None

Posted By Cats Meow in drugs.com on October 17, 2009 @ 12:00 am

I hate recommending it, but at such a high titration I think Methadone is your best and maybe only option at this point, it should do the job analgesia wise, and cloud your head less then OC. It's ...

Druginformer Identified Side Effects: None

Posted By bristolqueen in drugs.com on September 7, 2009 @ 12:00 am

Since palladone was removed form the market several years ago -I am curious. Was the Pallidone prescribed?

Druginformer Identified Side Effects: None

Posted By winnie.1963 in drugs.com on August 31, 2009 @ 12:00 am

Thank you for another helpful answer. I totally agree with the *each individual is different* approach but reading your experience has helped me put things into perspective. The assumption of "dr...

Druginformer Identified Side Effects: None

Posted By Businessman1 in drugs.com on August 27, 2009 @ 12:00 am

My dose won't help you because everyone is so different but as an FYI, I was taking about 30mg/day of the hydromorphone but was prescribed around 10mg. I also took oxycontin as well - a total of arou...

* Warning: The facts and figures contained in these reports are accurate to the best of our capability; however, our metrics are only meant to augment your medical knowledge, and should never be used as the sole basis for selecting a new medication. As with any medical decision, be sure to work with your doctor to ensure the best choices are made for your condition.

* About FAERS: The FDA Adverse Event Reporting System (FAERS) is used by FDA for activities such as looking for new safety concerns that might be related to a marketed product, evaluating a manufacturer's compliance to reporting regulations and responding to outside requests for information. Reporting of adverse events is a voluntary process, and not every report is sent to FDA and entered into FAERS. The FAERS database may contain duplicate reports, the report quality is variable, and many factors may influence reporting (e.g., media attention, length of time a drug is marketed, market share). For these reasons, FAERS case reports cannot be used to calculate incidence or estimates of risk for a particular product or compare risks between products.