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Amitriptyline Hydrochloride

Popular Brands: : Amitriptyline, Elavil, Amitriptyline Hydrochloride, Endep, Amitril
Official FDA Reports191,633
Social Media Events5,207
Total Posts9,988
Avg. Review Score3.50/ 5
Active Ingredients
  • Amitriptyline Hydrochloride
Approved Uses *

* Extracted from Drug Label

  • Accord Healthcare Inc
  • Ani Pharmaceuticals Inc
  • Astrazeneca Pharmaceuticals Lp
  • Bristol Myers Squibb Co
  • Hoffmann La Roche Inc
Show more manufacturers

  This report is for all products sharing this active ingredient. For more details, please use our Workbench for research on individual brands like Amitriptyline.

* Extracted from FDA Adverse Event Report


The quarterly trend chart illustrates changing levels of adverse events over time. Results from both the FDA Adverse Event Database (FAERS) and adverse events extracted from social media by Druginformer are plotted side-by-side for easy comparison.

The proportion of people completing user reviews who complained about a side effect.

The proportion of social media adverse event complaints for each adverse event type.

The proportion of FAERS (FDA) adverse event complaints for each adverse event type.

Amitriptyline Hydrochloride Side Effects

  Social Media
(Online Comments)
(Reports Submitted to FDA)
Side Effect On Drug
Reports % of
Alarm Reports % of

* DrugInformer calculates alarm using a proprietary algorithm. Alarm should not be taken as an ofiicial signal from the FDA or other regulatory entity.

User Voices

The following are comments from users that experienced side effects while taking Amitriptyline Hydrochloride

Disturbance In Attention

Works for the pain in lower left side but makes me very sleepy and disoriented only take when necessary.

Source: Elavil

View full report on Amitriptyline Hydrochloride related disturbance in attention

Did the author experience disturbance in attention while taking elavil?

What is this?

Food Craving

This is what I am currently taking. I can only tolerate 50 mg at this point because of the cravings for sweets that it causes. But its working for insomnia, stomach problems and pain.

Source: Elavil

View full report on Amitriptyline Hydrochloride related food craving

Did the author experience food craving while taking elavil?

What is this?


Made memories less bright reduced obcessive thoughts

Source: Elavil

View full report on Amitriptyline Hydrochloride related amnesia

Did the author experience amnesia while taking elavil?

What is this?

Tell us about your Experience with Amitriptyline Hydrochloride

Thank you for sharing your experience with us!

Share Your Experience

Druginformer Identified Side Effects: Somnolence, Abnormal dreams, Dry mouth

Effectiveness Rating:     Overall Rating:

Posted By Samantha on March 15, 2019 @ 9:07 pm

I’ve been on ami for over a year now to help with postshingles and endometriosis related pain. The tiredness, the lethargy, and grogginess took months to pass. I persisted with it and found taking it at night about 7pm was good as the main bulk of grogginess had passed by about 10am but for the first two months I was fast asleep within an hour of taking the drug (20mg at night). I have never been a dreamer, or at least I have never remembered anything I have dreamed. I just black out at night, but I started getting very vivid insane dreams, sometimes nightmares that I would wake up in a sweat shaking from. Most were just bizarre rather than frightening.

Druginformer Identified Side Effects: Dry mouth

Posted By Anonymous in askapatient.com on September 11, 2015 @ 12:00 am

Side Effects: Dry mouth in the mornings, nasal cavities are dry (which is ok with me), deeper sleep, I wake up ok, just feel like I have to take a minute or 2 to really clear the cobwebs. No change i...

Druginformer Identified Side Effects: Confusional state, Hot flush, Vomiting, Tinnitus, Tremor, Headache, Cold sweat

Posted By Anonymous in askapatient.com on August 15, 2015 @ 12:00 am

Side Effects: Terrible hot and cold sweats, tremors in hands, ringing ears, terrible sharp headache,confusion and constant throwing up. Had to stop taking immediately.

Druginformer Identified Side Effects: Dizziness, Lethargy, Memory impairment, Irregular sleep phase

Posted By Anonymous in askapatient.com on July 13, 2015 @ 12:00 am

Side Effects: Dizziness, lethargy, and almost blacking out. I was given this medication to help headaches, but instead I slept for 14 hours straight after taking the first dose. Felt very l...

Druginformer Identified Side Effects: Tremor

Posted By Anonymous in askapatient.com on June 16, 2015 @ 12:00 am

Side Effects: Dried out my mouth and gave me tremors in my hands. Out of a multitude of antidepressants that I have tried, elavil is the only one that has worked. Because of it I've been de...

Druginformer Identified Side Effects: Flatulence, Eructation, Vomiting, Walking disability, Discomfort, Respiration abnormal

Posted By Anonymous in askapatient.com on June 15, 2015 @ 12:00 am

... first day, could barely move, slept through the entire day, second day I was a bit better, but I was drunk, couldn't walk straight and had problems breathing. Third day I was sick again, and had gas t...

Druginformer Identified Side Effects: Somnolence

Posted By Anonymous in askapatient.com on May 21, 2015 @ 12:00 am

Side Effects: A bit groggy in the AM, otherwise no other negative effects. I was prescribed this due to my IBS. I had been struggling with mysterious stomach issues for the past several yea...

Druginformer Identified Side Effects: Constipation, Weight increased

Posted By Anonymous in askapatient.com on May 18, 2015 @ 12:00 am

Side Effects: Weight gain, severe constipation I loved that this medication stopped my nighttime bruxing. It also helped with sleep and was beginning to lift my mood but I couldn't tolerate...

Druginformer Identified Side Effects: Back pain, Food craving, Weight increased

Posted By Anonymous in askapatient.com on May 16, 2015 @ 12:00 am

... i was having a baby due to all the weight gained and cravings. the only time i had ever felt that way was 11yrs ago with my son. After not missing my cycle and not having a pos test i started thinking...

Druginformer Identified Side Effects: None

Posted By AmourDeMusique in fdb.rxlist.com on May 7, 2015 @ 12:00 am

Taking this medication for anxiety and panic disorder. It has lowered my anxiety levels significantly. I can focus better, and I'm also having fewer migraines. Previously taken many other Rx including...

Additional Drug Information

* Warning: The facts and figures contained in these reports are accurate to the best of our capability; however, our metrics are only meant to augment your medical knowledge, and should never be used as the sole basis for selecting a new medication. As with any medical decision, be sure to work with your doctor to ensure the best choices are made for your condition.

* About FAERS: The FDA Adverse Event Reporting System (FAERS) is used by FDA for activities such as looking for new safety concerns that might be related to a marketed product, evaluating a manufacturer's compliance to reporting regulations and responding to outside requests for information. Reporting of adverse events is a voluntary process, and not every report is sent to FDA and entered into FAERS. The FAERS database may contain duplicate reports, the report quality is variable, and many factors may influence reporting (e.g., media attention, length of time a drug is marketed, market share). For these reasons, FAERS case reports cannot be used to calculate incidence or estimates of risk for a particular product or compare risks between products.