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Cetirizine Hydrochloride

Popular Brands: : Zyrtec, Cetirizine, Cetirizine Hydrochloride, Children's Zyrtec Allergy, Cetirizine Hcl
Official FDA Reports153,910
Social Media Events7,767
Total Posts162,232
Avg. Review Score2.73/ 5
Active Ingredients
  • Cetirizine Hydrochloride
Brands and Other Names
Show more brands
  • 7-eleven
  • A P J Laboratories Limited
  • Aaron Industries, Inc.
  • Access Business Group Llc
  • American Sales Company
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  This report is for all products sharing this active ingredient. For more details, please use our Workbench for research on individual brands like Zyrtec.

* Extracted from FDA Adverse Event Report


The quarterly trend chart illustrates changing levels of adverse events over time. Results from both the FDA Adverse Event Database (FAERS) and adverse events extracted from social media by Druginformer are plotted side-by-side for easy comparison.

The proportion of people completing user reviews who complained about a side effect.

The proportion of social media adverse event complaints for each adverse event type.

The proportion of FAERS (FDA) adverse event complaints for each adverse event type.

Cetirizine Hydrochloride Side Effects

  Social Media
(Online Comments)
(Reports Submitted to FDA)
Side Effect On Drug
Reports % of
Alarm Reports % of

* DrugInformer calculates alarm using a proprietary algorithm. Alarm should not be taken as an ofiicial signal from the FDA or other regulatory entity.

User Voices

The following are comments from users that experienced side effects while taking Cetirizine Hydrochloride

Drug Tolerance

... about 12-16 hours after you take it. (That's why I take it at night before I go to bed.) Also, if you skip a dose, take it ASAP. Otherwise, your body will build up a type of tolerance to it and it wil...

Source: Zyrtec-D-Allergy-Medicine-review-3a051

View full report on Cetirizine Hydrochloride related drug tolerance

Did the author experience drug tolerance while taking zyrtec?

What is this?


can make some drowsy , other generics may be cheaper makes me less drowsy than others, helps topical and respiratory allergies, seems safe, can be taken daily if needed, no prescript...

Source: Cetirizine-Hydrochloride-Generic-Zyrte...

View full report on Cetirizine Hydrochloride related somnolence

Did the author experience somnolence while taking cetirizine hydrochloride?

What is this?


a few side effects: can cause drowsiness , can be higher in price 24 hr relief, helps w/ indoor and outdoor allergies, rx strength but is over the counter pros> Zyrtec allergy 24 hr...

Source: Zyrtec-Allergy-Medication-review-598d

View full report on Cetirizine Hydrochloride related somnolence

Did the author experience somnolence while taking zyrtec allergy?

What is this?

Tell us about your Experience with Cetirizine Hydrochloride

Thank you for sharing your experience with us!

Share Your Experience

Druginformer Identified Side Effects: Headache, Palpitations

Effectiveness Rating:     Overall Rating:

Posted By Andre on May 28, 2018 @ 8:48 am

Druginformer Identified Side Effects: Arthralgia

Effectiveness Rating:     Overall Rating:

Posted By Caty on May 31, 2017 @ 2:20 pm

first few weeks were effective and then one morning both knees and hips felt stiffness and achiness and fatigue and weakness... I am trying to rule out the side effects of the cetrizine hydrochloride...

Druginformer Identified Side Effects: Crying, Anxiety, Cardiac flutter, Depression, Disability

Posted By Anonymous in askapatient.com on September 9, 2015 @ 12:00 am

Side Effects: Heart palpitations, extreme anxiety, depression to the point I would burst into tears at random times. The active ingredient in this drug is cetirizine hydrochloride, and quit...

Druginformer Identified Side Effects: Tremor, Headache, Dizziness, Nausea, Pain, Chills, Vomiting, Loss of consciousness, Anxiety, Visual impairment, Euphoric mood, Dyspnoea, Insomnia, Pyrexia

Posted By Anonymous in askapatient.com on September 3, 2015 @ 12:00 am

Side Effects: Nausea and dizzy I cant go outside I fant every time I try..can eat cant sleep my nerves system cant stop shaking headache eyes blurry light headed cheats pain shortness of breath vomit...

Druginformer Identified Side Effects: Abnormal weight gain, Lethargy, Abdominal distension, Depression, Mood altered

Posted By Anonymous in askapatient.com on September 1, 2015 @ 12:00 am

... when I found this site and read all of the comments. I've been experiencing all of the same symptoms but never contributed them to taking Zyrtec. I've gained a lot of weight, I'm always bloated and ga...

Druginformer Identified Side Effects: Nasal dryness, Somnolence

Posted By Anonymous in askapatient.com on August 28, 2015 @ 12:00 am

Side Effects: Dry nose, nasal crusting, blood in nose, mild drowsiness This stuff works well on hay fever, maybe a little too well because I can only take half a pill and I'll be good for a...

Druginformer Identified Side Effects: Thought withdrawal, Increased appetite, Somnolence

Posted By Anonymous in askapatient.com on August 24, 2015 @ 12:00 am

... It's like my brain was sleeping. I gave up and slept for 2 hours after a full 8 hours of sleep the night before. I am normally a high energy person so I thought I was losing my mind until I realized...

Druginformer Identified Side Effects: Lethargy, Depression, Irritability

Posted By Anonymous in askapatient.com on August 15, 2015 @ 12:00 am

Side Effects: Irritability, severe depression, lethargy. On this for probably 15 years after trying so many others that either didn't do the job of muting the allergies or their side effect...

Druginformer Identified Side Effects: Sleep disorder, Nightmare, Screaming, Rash, Scratch, Haemorrhage, Seasonal allergy

Posted By Anonymous in askapatient.com on July 29, 2015 @ 12:00 am

Side Effects: My son was experiencing seasonal allergies and rashes due to moving into a rental that previously had cats and dogs. After many sleepless nights of scratching himself to the point of bl...

Druginformer Identified Side Effects: Hypersomnia, Pruritus, Mood swings, Anger, Depression, Insomnia

Posted By Anonymous in askapatient.com on July 16, 2015 @ 12:00 am

... of days ago, and many side effects described were eerily similar to what I've experienced these past couple of years. Bad temper, mood swings, depression, insomnia and sleeping too much were things I ...

Additional Drug Information

* Warning: The facts and figures contained in these reports are accurate to the best of our capability; however, our metrics are only meant to augment your medical knowledge, and should never be used as the sole basis for selecting a new medication. As with any medical decision, be sure to work with your doctor to ensure the best choices are made for your condition.

* About FAERS: The FDA Adverse Event Reporting System (FAERS) is used by FDA for activities such as looking for new safety concerns that might be related to a marketed product, evaluating a manufacturer's compliance to reporting regulations and responding to outside requests for information. Reporting of adverse events is a voluntary process, and not every report is sent to FDA and entered into FAERS. The FAERS database may contain duplicate reports, the report quality is variable, and many factors may influence reporting (e.g., media attention, length of time a drug is marketed, market share). For these reasons, FAERS case reports cannot be used to calculate incidence or estimates of risk for a particular product or compare risks between products.