Letrozole
Active Ingredients
- Letrozole
Manufacturers
- Mylan Pharmaceuticals Inc
- Novartis Pharmaceuticals Corp
This report is for all products sharing this active ingredient. For more details, please use our Workbench for research on individual brands like Femara.
Explanation
The quarterly trend chart illustrates changing levels of adverse events over time. Results from both the FDA Adverse Event Database (FAERS) and adverse events extracted from social media by Druginformer are plotted side-by-side for easy comparison.
The proportion of people completing user reviews who complained about a side effect.
The proportion of social media adverse event complaints for each adverse event type.
The proportion of FAERS (FDA) adverse event complaints for each adverse event type.
Letrozole Side Effects
| Social Media (Online Comments) |
FAERS (Reports Submitted to FDA) |
|||||||
|---|---|---|---|---|---|---|---|---|
| Side Effect | On Drug Label |
Overall Alarm |
Reports | % of Reports |
Alarm | Reports | % of Reports |
Alarm |
* DrugInformer calculates alarm using a proprietary algorithm. Alarm should not be taken as an ofiicial signal from the FDA or other regulatory entity.
Tell us about your Experience with Letrozole
Druginformer Identified Side Effects: Arthralgia, Fatigue, Somnolence, Weight increased
Posted By Anonymous in askapatient.com on August 21, 2015 @ 12:00 am
“Side Effects: Tired most of the time - even when I just wake up, I really wouldn't mind going back to sleep - joints hurt and hands won't bend all the way closed - at times I am awoken by joint pain,...”
Druginformer Identified Side Effects: Arthralgia, Carbohydrate craving, Fatigue, Joint swelling, Dry skin, Alopecia, Musculoskeletal pain, Eczema, Depression, Fungal infection, Insomnia, Oedema, Urinary tract infection, Weight increased
Posted By Anonymous in askapatient.com on August 19, 2015 @ 12:00 am
“Side Effects: Experienced weight gain, lack of energy, sweet cravings, slight depression (mostly due to side effects) severe joint pain that worsens the longer I take the drug, shoulder pain, trouble...”
Druginformer Identified Side Effects: Arthralgia, Fatigue, Cough, Insomnia, Somnolence, Weight increased
Posted By Anonymous in askapatient.com on July 27, 2015 @ 12:00 am
“... very active and high energy person, until I started taking Anastrazole. The arthritis like pain in my knees became unbearable so my doc switched me to Letrozole/Femara, pain in knees continues and I ...”
Druginformer Identified Side Effects: Back pain, Alopecia, Hyperhidrosis, Insomnia, Mental impairment, Muscle spasms, Pain in extremity, Somnolence, Weight increased
Posted By Anonymous in askapatient.com on July 13, 2015 @ 12:00 am
“Side Effects: 24/7 profuse sweating. Insomnia, severe muscle cramps in abdominal area, severe lower back pain, hip and left leg pain. Weight gain, no motivation, tired all the time. Hair thinning.
Druginformer Identified Side Effects: Neck pain, Blood cholesterol increased, Depression, Hyperhidrosis, Joint stiffness
Posted By Anonymous in askapatient.com on July 11, 2015 @ 12:00 am
“Side Effects: Extreme Joint stiffness, depression, severe sweats even when sitting under a fan and a/c, pain in neck and shoulder on side of surgery. Cholesterol went up significantly in first month ...”
Druginformer Identified Side Effects: Fatigue, Bone pain, Vomiting, Anxiety, Cough, Depression, Disturbance in attention, Insomnia, Joint stiffness, Pain in extremity, Trigger finger
Posted By Anonymous in askapatient.com on July 3, 2015 @ 12:00 am
“
Druginformer Identified Side Effects: Fatigue, Pain, Alopecia, Insomnia
Posted By Anonymous in askapatient.com on June 29, 2015 @ 12:00 am
“Side Effects: No energy, hair falling out pain in muscles and bones that strong prescription pain medication doesn't ever relieve also cant sleep. ”
Druginformer Identified Side Effects: Back pain, Anxiety, Apathy, Disturbance in attention, Irritability
Posted By Anonymous in askapatient.com on June 29, 2015 @ 12:00 am
“Side Effects: Inability to concentrate, short temper, inability to complete work, pain in back, shoulders, arms and sometimes legs. Definite lack of motivation. Difficulty getting to sleep at night ...”
Druginformer Identified Side Effects: Dizziness, Alopecia, Blood cholesterol increased
Posted By Anonymous in askapatient.com on June 29, 2015 @ 12:00 am
“Side Effects: Took femara for a year- no side effects. Was switched to generic letrozole when I went on Medicare.Worst side effect for me has been lightheadedness and often feeling slightly and const...”
Druginformer Identified Side Effects: Headache, Arthralgia, Neuropathy peripheral, Alopecia, Weight increased, Hot flush
Posted By Anonymous in askapatient.com on June 25, 2015 @ 12:00 am
“Side Effects: 40# weight gain. Headaches. Bone & joint pain. Hair loss. Neuropathy in hands & feet. hot flashes constantly. After 3 yrs 7 months the effects have not improved.. I have til M...”
Additional Drug Information
* Warning: The facts and figures contained in these reports are accurate to the best of our capability; however, our metrics are only meant to augment your medical knowledge, and should never be used as the sole basis for selecting a new medication. As with any medical decision, be sure to work with your doctor to ensure the best choices are made for your condition.
* About FAERS: The FDA Adverse Event Reporting System (FAERS) is used by FDA for activities such as looking for new safety concerns that might be related to a marketed product, evaluating a manufacturer's compliance to reporting regulations and responding to outside requests for information. Reporting of adverse events is a voluntary process, and not every report is sent to FDA and entered into FAERS. The FAERS database may contain duplicate reports, the report quality is variable, and many factors may influence reporting (e.g., media attention, length of time a drug is marketed, market share). For these reasons, FAERS case reports cannot be used to calculate incidence or estimates of risk for a particular product or compare risks between products.
User Voices
The following are comments from users that experienced side effects while taking Letrozole
Musculoskeletal Discomfort
“... Femara is one of three aromatase inhibitors on the market (Arimidex, Aromasin and Femara) . They are all expensive (about $500 per month) and all cause severe joint and muscle aches . They also cause ...”
Source: Femara-Hormone-Blocker-review-09f94
View full report on Letrozole related musculoskeletal discomfort
Did the author experience musculoskeletal discomfort while taking femara?
What is this?Bone Loss
“... aromatase inhibitors on the market (Arimidex, Aromasin and Femara) . They are all expensive (about $500 per month) and all cause severe joint and muscle aches. They also cause bone loss . Managing the...”
Source: Femara-Hormone-Blocker-review-09f94
View full report on Letrozole related bone loss
Did the author experience bone loss while taking femara?
What is this?Mood Swings
“... issues I have because of a luteal phase defect. Previously I had tried Clomid unsuccessfully and had unpleasant side effects. I became grumpy on the Clomid and had mood swings often. After three mo...”
Source: Femara-Hormone-Blocker-review-a74411
View full report on Letrozole related mood swings
Did the author experience mood swings while taking femara?
What is this?