Letrozole
Active Ingredients
- Letrozole
Manufacturers
- Mylan Pharmaceuticals Inc
- Novartis Pharmaceuticals Corp
This report is for all products sharing this active ingredient. For more details, please use our Workbench for research on individual brands like Femara.
Explanation
The quarterly trend chart illustrates changing levels of adverse events over time. Results from both the FDA Adverse Event Database (FAERS) and adverse events extracted from social media by Druginformer are plotted side-by-side for easy comparison.
The proportion of people completing user reviews who complained about a side effect.
The proportion of social media adverse event complaints for each adverse event type.
The proportion of FAERS (FDA) adverse event complaints for each adverse event type.
Letrozole Side Effects
| Social Media (Online Comments) |
FAERS (Reports Submitted to FDA) |
|||||||
|---|---|---|---|---|---|---|---|---|
| Side Effect | On Drug Label |
Overall Alarm |
Reports | % of Reports |
Alarm | Reports | % of Reports |
Alarm |
* DrugInformer calculates alarm using a proprietary algorithm. Alarm should not be taken as an ofiicial signal from the FDA or other regulatory entity.
Tell us about your Experience with Letrozole
Druginformer Identified Side Effects: Sleep disorder, Insomnia, Joint stiffness, Muscle spasms, Trigger finger, Musculoskeletal discomfort
Posted By Linda in fdb.rxlist.com on March 3, 2008 @ 12:00 am
“... due to aching muscles and cramps in feet and legs. I have a trigger finger and hands are very stiff in the morning. Mobility after setting a long period of time or sleeping is very difficult. I tak...”
Druginformer Identified Side Effects: Weight decreased, Weight increased
Posted By pekinese2001 in fdb.rxlist.com on March 3, 2008 @ 12:00 am
“I had made a comment before about weight gain after using Arimidex. I have since been able to lose 25 lbs. by eating a raw veggie salad for dinner with no cheese or eggs and by working up to walking ...”
Druginformer Identified Side Effects: Arthralgia, Hypoaesthesia, Amnesia, Weight increased
Posted By Anonymous in askapatient.com on February 28, 2008 @ 12:00 am
“Side Effects: joint pain, loss of memory, weight gain. Numbing on right side in the a.m. Took tamoxfin for 2years and suffered joint pain, but the femera is worse. I am worried that the pa...”
Druginformer Identified Side Effects: Arthralgia, Fatigue, Visual impairment, Dry eye, Insomnia, Pain in extremity, Weight increased, Weight loss poor
Posted By Anonymous in askapatient.com on February 26, 2008 @ 12:00 am
“Side Effects: Arthalgia, my hands hurt all the time now & feet hurt all the time; unable to lose weight I have gained; recently have had blurred vison & very dry eyes; trouble sleeping; no energy or ...”
Druginformer Identified Side Effects: Fatigue, Trigger finger
Posted By Shelley in fdb.rxlist.com on February 25, 2008 @ 12:00 am
“... me from breast cancer but also other cancers. I have learned that this drug is a steroid and that is the reason for the weight and muscle gain. Also have had trigger finger, and been tierd. I am ...”
Druginformer Identified Side Effects: Photopsia
Posted By mary in fdb.rxlist.com on February 22, 2008 @ 12:00 am
“Have been on Arimidex for 2 months following a L mastectomy. After reading all the other reviews, I consider myself lucky - no bone pain, flashes, etc. However, I have gained almost 15 lbs in these tw...”
Druginformer Identified Side Effects: Trigger finger, Hot flush
Posted By JoAnn in fdb.rxlist.com on February 19, 2008 @ 12:00 am
“I have been on Arimidex for almost 4 years, I did have trigger finger, and had to have carpal tunnel surgery. I do get alot of hot flashes through-out the day and night and very tired. But the cance...”
Druginformer Identified Side Effects: Arthralgia, Vulvovaginal dryness, Myalgia, Disturbance in attention
Posted By Anonymous in askapatient.com on February 18, 2008 @ 12:00 am
“Side Effects: horrible muscle and joint pain, "brain fog", vaginal dryness Six months after completing 5 years on Femara, I am ready for my first half marathon :) All the side effects are g...”
Druginformer Identified Side Effects: Arthralgia, Pain, Myalgia, Memory impairment, Musculoskeletal pain, Menopause, Insomnia, Loss of libido, Osteoarthritis, Hot flush
Posted By Anonymous in askapatient.com on February 16, 2008 @ 12:00 am
“Side Effects: I took Tamoxifen for 5 years and Femara for 3. I was having joint and muscle pain, asked my oncologist if I could quit, he agreed. All other symptoms could be attributed to menopause ma...”
Druginformer Identified Side Effects: Nausea, Crying, Obesity, Retirement, Disability, Disturbance in attention, Suicidal behaviour
Posted By Anonymous in askapatient.com on February 15, 2008 @ 12:00 am
“Side Effects: No hair loss or nausea so far, but all the other severe side effects common to all the comments on this site. I used to win awards for my work, but am forced to (I hope) retire early fr...”
Additional Drug Information
* Warning: The facts and figures contained in these reports are accurate to the best of our capability; however, our metrics are only meant to augment your medical knowledge, and should never be used as the sole basis for selecting a new medication. As with any medical decision, be sure to work with your doctor to ensure the best choices are made for your condition.
* About FAERS: The FDA Adverse Event Reporting System (FAERS) is used by FDA for activities such as looking for new safety concerns that might be related to a marketed product, evaluating a manufacturer's compliance to reporting regulations and responding to outside requests for information. Reporting of adverse events is a voluntary process, and not every report is sent to FDA and entered into FAERS. The FAERS database may contain duplicate reports, the report quality is variable, and many factors may influence reporting (e.g., media attention, length of time a drug is marketed, market share). For these reasons, FAERS case reports cannot be used to calculate incidence or estimates of risk for a particular product or compare risks between products.
User Voices
The following are comments from users that experienced side effects while taking Letrozole
Musculoskeletal Discomfort
“... Femara is one of three aromatase inhibitors on the market (Arimidex, Aromasin and Femara) . They are all expensive (about $500 per month) and all cause severe joint and muscle aches . They also cause ...”
Source: Femara-Hormone-Blocker-review-09f94
View full report on Letrozole related musculoskeletal discomfort
Did the author experience musculoskeletal discomfort while taking femara?
What is this?Bone Loss
“... aromatase inhibitors on the market (Arimidex, Aromasin and Femara) . They are all expensive (about $500 per month) and all cause severe joint and muscle aches. They also cause bone loss . Managing the...”
Source: Femara-Hormone-Blocker-review-09f94
View full report on Letrozole related bone loss
Did the author experience bone loss while taking femara?
What is this?Mood Swings
“... issues I have because of a luteal phase defect. Previously I had tried Clomid unsuccessfully and had unpleasant side effects. I became grumpy on the Clomid and had mood swings often. After three mo...”
Source: Femara-Hormone-Blocker-review-a74411
View full report on Letrozole related mood swings
Did the author experience mood swings while taking femara?
What is this?