DrugInformer Search

Letrozole

Popular Brands: : Femara, Letrozole, Cgs 20267
Official FDA Reports48,535
Social Media Events8,267
Total Posts3,138
Avg. Review Score2.88/ 5
Active Ingredients
  • Letrozole
Brands and Other Names
Manufacturers
  • Mylan Pharmaceuticals Inc
  • Novartis Pharmaceuticals Corp

  This report is for all products sharing this active ingredient. For more details, please use our Workbench for research on individual brands like Femara.

* Extracted from FDA Adverse Event Report

Explanation

The quarterly trend chart illustrates changing levels of adverse events over time. Results from both the FDA Adverse Event Database (FAERS) and adverse events extracted from social media by Druginformer are plotted side-by-side for easy comparison.


The proportion of people completing user reviews who complained about a side effect.

The proportion of social media adverse event complaints for each adverse event type.

The proportion of FAERS (FDA) adverse event complaints for each adverse event type.


Letrozole Side Effects

  Social Media
(Online Comments)
FAERS
(Reports Submitted to FDA)
Side Effect On Drug
Label
Overall
Alarm
Reports % of
Reports
Alarm Reports % of
Reports
Alarm

* DrugInformer calculates alarm using a proprietary algorithm. Alarm should not be taken as an ofiicial signal from the FDA or other regulatory entity.


User Voices

The following are comments from users that experienced side effects while taking Letrozole

Musculoskeletal Discomfort

... Femara is one of three aromatase inhibitors on the market (Arimidex, Aromasin and Femara) . They are all expensive (about $500 per month) and all cause severe joint and muscle aches . They also cause ...


Source: Femara-Hormone-Blocker-review-09f94

View full report on Letrozole related musculoskeletal discomfort

Did the author experience musculoskeletal discomfort while taking femara?

What is this?

Bone Loss

... aromatase inhibitors on the market (Arimidex, Aromasin and Femara) . They are all expensive (about $500 per month) and all cause severe joint and muscle aches. They also cause bone loss . Managing the...


Source: Femara-Hormone-Blocker-review-09f94

View full report on Letrozole related bone loss

Did the author experience bone loss while taking femara?

What is this?

Mood Swings

... issues I have because of a luteal phase defect. Previously I had tried Clomid unsuccessfully and had unpleasant side effects. I became grumpy on the Clomid and had mood swings often. After three mo...


Source: Femara-Hormone-Blocker-review-a74411

View full report on Letrozole related mood swings

Did the author experience mood swings while taking femara?

What is this?

Tell us about your Experience with Letrozole

Thank you for sharing your experience with us!

Share Your Experience

Druginformer Identified Side Effects: Fatigue, Pain, Abnormal weight gain, Disturbance in attention, Hot flush

Posted By Anonymous in askapatient.com on June 23, 2015 @ 12:00 am

... Femara about two months ago. I haven't lost any weight, but I will work on that. The hot flashes are gone. I can sleep without waking up in a pool of sweat. I am not as bone tired as I was. I thi...

Druginformer Identified Side Effects: Arthralgia, Back pain, Bone pain, Lethargy, Insomnia, Trigger finger, Weight increased, Abasia, Hot flush

Posted By Anonymous in askapatient.com on June 21, 2015 @ 12:00 am

... get in and out of vehicles,etc. The Good News! After being taken off Letrozole as well as Anastrozole, I was put on Tamoxifen. It changed my life! All my bone and joint pain disappeared within weeks. ...

Druginformer Identified Side Effects: Arthralgia, Bone pain, Hyperhidrosis, Insomnia, Loss of libido, Somnolence, Vaginal infection, Weight increased, Hot flush

Posted By Anonymous in askapatient.com on June 17, 2015 @ 12:00 am

Side Effects: Severe joint and bone pain, weight gain, fatigue, insomnia, severe hot flashes and sweating, mostly of head and face, thinned vaginal tissue, nonexistent libido. I still work ...

Druginformer Identified Side Effects: Arthralgia, Crying, Hot flush

Posted By Anonymous in askapatient.com on June 13, 2015 @ 12:00 am

Side Effects: After taking letroxole for 4 weeks the body aches were horrible. Hot flashes and crying for no reason was horrible too. My oncologist changed to anatroxole. After reading their side eff...

Druginformer Identified Side Effects: Arthralgia, Bone pain, Anger, Depressed mood, Anxiety, Disturbance in attention, Irritability, Somnolence, Swelling

Posted By Anonymous in askapatient.com on June 8, 2015 @ 12:00 am

Side Effects: Have had brain fog lack of concentration, fatigue, bone pain, wrist pain and swelling, and other symptoms also. I have been unable to work due to this and feel depressed anxious and get...

Druginformer Identified Side Effects: Arthralgia, Fatigue, Influenza, Memory impairment, Disturbance in attention, Muscle spasms

Posted By Anonymous in askapatient.com on June 5, 2015 @ 12:00 am

... feet and leg cramps. One day energetic the next i feel line a truck hit me and exhausted. Fun to work at a high pressure job like this. Started on Arimidex first but painful joints and muscle cramps m...

Druginformer Identified Side Effects: Cardiovascular disorder, Lipids

Posted By Anonymous in fdb.rxlist.com on May 30, 2015 @ 12:00 am

... After 17 months on the drug, my lipids are now very high, which I now learned is another side effect. I've never had a cholesterol problem. Must choose to discontinue or have heart problems....

Druginformer Identified Side Effects: Dysuria, Hot flush

Posted By Anonymous in askapatient.com on May 21, 2015 @ 12:00 am

Side Effects: Hot flushes increasing again after 12 months use and now waking in night with painful flush through clitoris, and external soft tissue around vagina.. Same pain urinating

Druginformer Identified Side Effects: Burning sensation, Difficulty concentrating, Adrenal disorder, Trigger finger

Posted By Anonymous in askapatient.com on May 19, 2015 @ 12:00 am

... pull my pants up. Took 800mg ibuprofen. Went on tamoxifen. No problems. Now found out I have more tumors. Been on Letrizole (Femera) for 3 months. Bottoms of feet and hands burning. Paint but j...

Druginformer Identified Side Effects: Arthralgia, Disturbance in attention, Somnolence, Trigger finger, Weight increased

Posted By Anonymous in askapatient.com on May 14, 2015 @ 12:00 am

Side Effects: Joint Ache, Trigger Finger - Tiredness - Foggy Brain - Weight Gain I am pleased to know l am not the only one having these symptoms, l have told my Oncologist, but they want m...


Additional Drug Information


* Warning: The facts and figures contained in these reports are accurate to the best of our capability; however, our metrics are only meant to augment your medical knowledge, and should never be used as the sole basis for selecting a new medication. As with any medical decision, be sure to work with your doctor to ensure the best choices are made for your condition.

* About FAERS: The FDA Adverse Event Reporting System (FAERS) is used by FDA for activities such as looking for new safety concerns that might be related to a marketed product, evaluating a manufacturer's compliance to reporting regulations and responding to outside requests for information. Reporting of adverse events is a voluntary process, and not every report is sent to FDA and entered into FAERS. The FAERS database may contain duplicate reports, the report quality is variable, and many factors may influence reporting (e.g., media attention, length of time a drug is marketed, market share). For these reasons, FAERS case reports cannot be used to calculate incidence or estimates of risk for a particular product or compare risks between products.