DrugInformer Search

Letrozole

Popular Brands: : Femara, Letrozole, Cgs 20267
Official FDA Reports48,535
Social Media Events8,267
Total Posts3,138
Avg. Review Score2.88/ 5
Active Ingredients
  • Letrozole
Brands and Other Names
Manufacturers
  • Mylan Pharmaceuticals Inc
  • Novartis Pharmaceuticals Corp

  This report is for all products sharing this active ingredient. For more details, please use our Workbench for research on individual brands like Femara.

* Extracted from FDA Adverse Event Report

Explanation

The quarterly trend chart illustrates changing levels of adverse events over time. Results from both the FDA Adverse Event Database (FAERS) and adverse events extracted from social media by Druginformer are plotted side-by-side for easy comparison.


The proportion of people completing user reviews who complained about a side effect.

The proportion of social media adverse event complaints for each adverse event type.

The proportion of FAERS (FDA) adverse event complaints for each adverse event type.


Letrozole Side Effects

  Social Media
(Online Comments)
FAERS
(Reports Submitted to FDA)
Side Effect On Drug
Label
Overall
Alarm
Reports % of
Reports
Alarm Reports % of
Reports
Alarm

* DrugInformer calculates alarm using a proprietary algorithm. Alarm should not be taken as an ofiicial signal from the FDA or other regulatory entity.


User Voices

The following are comments from users that experienced side effects while taking Letrozole

Musculoskeletal Discomfort

... Femara is one of three aromatase inhibitors on the market (Arimidex, Aromasin and Femara) . They are all expensive (about $500 per month) and all cause severe joint and muscle aches . They also cause ...


Source: Femara-Hormone-Blocker-review-09f94

View full report on Letrozole related musculoskeletal discomfort

Did the author experience musculoskeletal discomfort while taking femara?

What is this?

Bone Loss

... aromatase inhibitors on the market (Arimidex, Aromasin and Femara) . They are all expensive (about $500 per month) and all cause severe joint and muscle aches. They also cause bone loss . Managing the...


Source: Femara-Hormone-Blocker-review-09f94

View full report on Letrozole related bone loss

Did the author experience bone loss while taking femara?

What is this?

Mood Swings

... issues I have because of a luteal phase defect. Previously I had tried Clomid unsuccessfully and had unpleasant side effects. I became grumpy on the Clomid and had mood swings often. After three mo...


Source: Femara-Hormone-Blocker-review-a74411

View full report on Letrozole related mood swings

Did the author experience mood swings while taking femara?

What is this?

Tell us about your Experience with Letrozole

Thank you for sharing your experience with us!

Share Your Experience

Druginformer Identified Side Effects: None

Posted By Mskittylitter in fdb.rxlist.com on September 19, 2015 @ 12:00 am

I've only been on this drug for 6 months and I stopped it 2 weeks ago I cannot bear the joint and bone pain that it has caused. With the percentage under 5% that I'll have a reoccurrence of cancer by...

Druginformer Identified Side Effects: Arthralgia, Back pain, Fatigue, Pruritus, Alopecia, Amnesia, Loss of libido, Vaginal infection, Weight increased, Hot flush

Posted By Anonymous in askapatient.com on September 15, 2015 @ 12:00 am

... especially knees shoulders, lower back pain, short term memory affected. Hair thinner on top. Scalp extremely itchy. Vaginal area extremely itchy. No libido. Weight gain. aches all over.. Feel like a...

Druginformer Identified Side Effects: Bone pain, Myalgia, Cough, Insomnia, Throat tightness

Posted By Anonymous in askapatient.com on September 15, 2015 @ 12:00 am

Side Effects: Massive muscle and bone pain. Trouble swallowing, cough, insomnia.

Druginformer Identified Side Effects: Hyperhidrosis, Fatigue, Pain, Amnesia, Pain in extremity

Posted By Anonymous in askapatient.com on September 14, 2015 @ 12:00 am

... side effects hit me like a Mack truck! Severe foot pain to the point that I limp. Body literally hurts, every bone, every joint, dare I say my hair hurts too!! Profuse sweating, memory loss, extreme f...

Druginformer Identified Side Effects: Nausea, Lethargy, Anxiety, Atrophic vulvovaginitis, Apathy, Confusional state, Disturbance in attention, Loss of libido

Posted By Anonymous in askapatient.com on September 8, 2015 @ 12:00 am

Side Effects: Nausea, didn't want to do anything, not myself, emotional flatness, no drive, brain fog, periods of extreme anxiety, vaginal atrophy, no sex drive. Feels like sciatica in left...

Druginformer Identified Side Effects: Arthralgia, Vulvovaginal dryness, Amnesia, Weight increased, Hot flush

Posted By Anonymous in askapatient.com on September 6, 2015 @ 12:00 am

Side Effects: achy joints particularly feet, hot flashes, extreme vaginal dryness, weight gain & memory loss especially short term

Druginformer Identified Side Effects: None

Posted By Micheles in fdb.rxlist.com on August 31, 2015 @ 12:00 am

After being on Arimidex for almost a year, I had such tremendous breast pain following lumpectomy (both breasts) and lymph node (1) removal on each side, that I was advised to go off for a month, and ...

Druginformer Identified Side Effects: Arthralgia, Fatigue, Somnolence, Weight increased

Posted By Anonymous in askapatient.com on August 21, 2015 @ 12:00 am

Side Effects: Tired most of the time - even when I just wake up, I really wouldn't mind going back to sleep - joints hurt and hands won't bend all the way closed - at times I am awoken by joint pain,...

Druginformer Identified Side Effects: Arthralgia, Carbohydrate craving, Fatigue, Joint swelling, Dry skin, Alopecia, Musculoskeletal pain, Eczema, Depression, Fungal infection, Insomnia, Oedema, Urinary tract infection, Weight increased

Posted By Anonymous in askapatient.com on August 19, 2015 @ 12:00 am

Side Effects: Experienced weight gain, lack of energy, sweet cravings, slight depression (mostly due to side effects) severe joint pain that worsens the longer I take the drug, shoulder pain, trouble...

Druginformer Identified Side Effects: Arthralgia, Fatigue, Cough, Insomnia, Somnolence, Weight increased

Posted By Anonymous in askapatient.com on July 27, 2015 @ 12:00 am

... very active and high energy person, until I started taking Anastrazole. The arthritis like pain in my knees became unbearable so my doc switched me to Letrozole/Femara, pain in knees continues and I ...


Additional Drug Information


* Warning: The facts and figures contained in these reports are accurate to the best of our capability; however, our metrics are only meant to augment your medical knowledge, and should never be used as the sole basis for selecting a new medication. As with any medical decision, be sure to work with your doctor to ensure the best choices are made for your condition.

* About FAERS: The FDA Adverse Event Reporting System (FAERS) is used by FDA for activities such as looking for new safety concerns that might be related to a marketed product, evaluating a manufacturer's compliance to reporting regulations and responding to outside requests for information. Reporting of adverse events is a voluntary process, and not every report is sent to FDA and entered into FAERS. The FAERS database may contain duplicate reports, the report quality is variable, and many factors may influence reporting (e.g., media attention, length of time a drug is marketed, market share). For these reasons, FAERS case reports cannot be used to calculate incidence or estimates of risk for a particular product or compare risks between products.