DrugInformer Search

Naphazoline Hydrochloride; Pheniramine Maleate

Popular Brands: : Opcon-a, Visine-a, Naphcon-a, Naphcon A, Visine A
Official FDA Reports2,324
Social Media Events60
Total Posts1,812
Avg. Review Score3.72/ 5
Active Ingredients
  • Naphazoline Hydrochloride; Pheniramine Maleate
Approved Uses *

* Extracted from Drug Label

  • Alcon Laboratories Inc
  • Alcon Laboratories, Inc.
  • Altaire Pharmaceuticals Inc
  • Altaire Pharmaceuticals Inc.
  • Bausch And Lomb Inc
Show more manufacturers

  This report is for all products sharing this active ingredient. For more details, please use our Workbench for research on individual brands like Opcon-a.

* Extracted from FDA Adverse Event Report


The quarterly trend chart illustrates changing levels of adverse events over time. Results from both the FDA Adverse Event Database (FAERS) and adverse events extracted from social media by Druginformer are plotted side-by-side for easy comparison.

The proportion of people completing user reviews who complained about a side effect.

The proportion of social media adverse event complaints for each adverse event type.

The proportion of FAERS (FDA) adverse event complaints for each adverse event type.

Naphazoline Hydrochloride; Pheniramine Maleate Side Effects

  Social Media
(Online Comments)
(Reports Submitted to FDA)
Side Effect On Drug
Reports % of
Alarm Reports % of

* DrugInformer calculates alarm using a proprietary algorithm. Alarm should not be taken as an ofiicial signal from the FDA or other regulatory entity.

User Voices

The following are comments from users that experienced side effects while taking Naphazoline Hydrochloride; Pheniramine Maleate

Ocular Hyperaemia

... the day. Since I always have red eyes when I wake up, I started using the Visine daily and I continue to do so. The packaging does say that overuse may cause more eye redness (rebound effects), but af...

Source: Visine-A-C-Eye-Drops-review-8050

View full report on Naphazoline Hydrochloride; Pheniramine Maleate related ocular hyperaemia

Did the author experience ocular hyperaemia while taking visine-a?

What is this?

Rebound Effect

Potential for rebound effects Cheap when purchased as 2+2, Gets The Red Out!, Soothes Tired Eyes An Insomniac's Morning Essential Red, bloodshot eyes are not the most fun thi...

Source: Visine-A-C-Eye-Drops-review-8050

View full report on Naphazoline Hydrochloride; Pheniramine Maleate related rebound effect

Did the author experience rebound effect while taking visine-a?

What is this?


... drops per eye are all you require in order to clear up redness and eliminate the itch factor. When I dispense Visine A Drops into my eye, well.... they cause a painful stinging and burning sensation....

Source: Visine-A-Antihistamine-Redness-Relieve...

View full report on Naphazoline Hydrochloride; Pheniramine Maleate related pain

Did the author experience pain while taking visine-a?

What is this?

Tell us about your Experience with Naphazoline Hydrochloride; Pheniramine Maleate

Thank you for sharing your experience with us!

Share Your Experience

Druginformer Identified Side Effects: Vision blurred

Posted By boymom2 in fdb.rxlist.com on July 17, 2014 @ 12:00 am

ought Opcon A for allergies. Eyes dilated so bad vision was effected. Will never buy again. Do not recommend.

Druginformer Identified Side Effects: Tremor, Pruritus, Nervousness, Pupillary reflex impaired, Vision blurred

Posted By ch in fdb.rxlist.com on February 11, 2014 @ 12:00 am

Itchy, red left eye dilated pupil, therefore blurring vision within minutes of use. The other eye had no reaction. Shaky and nervousness after 20 minutes.

Druginformer Identified Side Effects: None

Posted By Anonymous in drugs.com on February 8, 2013 @ 12:00 am

After contracting Lyme disease my immune system became weaker and eye allergy is now a continual issue. Opcon-A has made the difference. My current problem has been going to work in the morni...

Druginformer Identified Side Effects: Pruritus

Posted By LindsayJ in fdb.rxlist.com on July 21, 2012 @ 12:00 am

I love this stuff! My allergies are horrendous and these drops are the only thing to give me relief at night. I use them before bed to stop the redness and itchiness I experience. My doctor suggested ...

Druginformer Identified Side Effects: None

Posted By Anonymous in www.everydayhealth.com on June 6, 2012 @ 12:00 am

I ve been using it for five or six years daily and I haven t had any side effects. it keeps my eyes clean and bright. before it I used to get some bad allergies in some months of the year.

Druginformer Identified Side Effects: Pruritus

Posted By Gordon in fdb.rxlist.com on May 21, 2012 @ 12:00 am

Worked great itching in eye went away after use. Plan on using again.

Druginformer Identified Side Effects: None

Posted By Bryan-Carey in viewpoints.com on February 20, 2012 @ 12:00 am

ausch & Lomb Opcon-A Eye Drops Return the Eyes to Health Allergy sufferers usually have problems with the sinuses and nose more than anything, but some experience problems elsewhere on the body. The ...

Druginformer Identified Side Effects: Pain

Posted By rnptx in viewpoints.com on August 12, 2011 @ 12:00 am

... matter that falls into them. I had some awful eye itching from allergies, and my mom pulled this product out of her purse and offered it to me. As another reviewer mentioned, it did sting a little bit...

Druginformer Identified Side Effects: Dizziness, Nausea, Hyperhidrosis

Posted By Anonymous in fdb.rxlist.com on August 11, 2011 @ 12:00 am

It relieved the itching but about 2 hours after using the drops severe dizziness, nausea and sweating set in. The dizziness remained for over 24 hours. Was unable to drive or go to work.

Druginformer Identified Side Effects: None

Posted By pcrhimer in viewpoints.com on August 9, 2011 @ 12:00 am

A 'must have' if you suffer from itchy eyes... This product is an absolute "must have" for me. I wouldn't consider running out of it and not replacing it. I have severe allergies, and I s...

Additional Drug Information

* Warning: The facts and figures contained in these reports are accurate to the best of our capability; however, our metrics are only meant to augment your medical knowledge, and should never be used as the sole basis for selecting a new medication. As with any medical decision, be sure to work with your doctor to ensure the best choices are made for your condition.

* About FAERS: The FDA Adverse Event Reporting System (FAERS) is used by FDA for activities such as looking for new safety concerns that might be related to a marketed product, evaluating a manufacturer's compliance to reporting regulations and responding to outside requests for information. Reporting of adverse events is a voluntary process, and not every report is sent to FDA and entered into FAERS. The FAERS database may contain duplicate reports, the report quality is variable, and many factors may influence reporting (e.g., media attention, length of time a drug is marketed, market share). For these reasons, FAERS case reports cannot be used to calculate incidence or estimates of risk for a particular product or compare risks between products.