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Metformin Hydrochloride; Pioglitazone Hydrochloride

Popular Brands: : Actoplus Met, Pioglitazone Hydrochloride And Metformin Hydrochloride, Actoplus Met Xr, Pioglitazone And Metformin, Pioglitazone And Metformin Hydrocholride
Official FDA Reports3,807
Social Media Events107
Total Posts596
Avg. Review Score3.69/ 5
Active Ingredients
  • Metformin Hydrochloride; Pioglitazone Hydrochloride
Manufacturers
  • Avkare, Inc.
  • Mylan Pharmaceuticals Inc
  • Sandoz Inc
  • Takeda Pharmaceuticals Usa Inc
  • Torrent Pharmaceuticals Limited

  This report is for all products sharing this active ingredient. For more details, please use our Workbench for research on individual brands like Actoplus Met.

* Extracted from FDA Adverse Event Report

Explanation

The quarterly trend chart illustrates changing levels of adverse events over time. Results from both the FDA Adverse Event Database (FAERS) and adverse events extracted from social media by Druginformer are plotted side-by-side for easy comparison.


The proportion of people completing user reviews who complained about a side effect.

The proportion of social media adverse event complaints for each adverse event type.

The proportion of FAERS (FDA) adverse event complaints for each adverse event type.


Metformin Hydrochloride; Pioglitazone Hydrochloride Side Effects

  Social Media
(Online Comments)
FAERS
(Reports Submitted to FDA)
Side Effect On Drug
Label
Overall
Alarm
Reports % of
Reports
Alarm Reports % of
Reports
Alarm

* DrugInformer calculates alarm using a proprietary algorithm. Alarm should not be taken as an ofiicial signal from the FDA or other regulatory entity.


User Voices

The following are comments from users that experienced side effects while taking Metformin Hydrochloride; Pioglitazone Hydrochloride

Feeling Of Despair

This medication increased my appetite, gave me diarrhea and made me feel horrible !


Source: Actoplus MET oral : User Ratings cover...

View full report on Metformin Hydrochloride; Pioglitazone Hydrochloride related feeling of despair

Did the author experience feeling of despair while taking actoplus met?

What is this?

Diarrhoea

This medication increased my appetite, gave me diarrhea and made me feel horrible!


Source: Actoplus MET oral : User Ratings cover...

View full report on Metformin Hydrochloride; Pioglitazone Hydrochloride related diarrhoea

Did the author experience diarrhoea while taking actoplus met?

What is this?

Decreased Appetite

This medication increased my appetite , gave me diarrhea and made me feel horrible!


Source: Actoplus MET oral : User Ratings cover...

View full report on Metformin Hydrochloride; Pioglitazone Hydrochloride related decreased appetite

Did the author experience decreased appetite while taking actoplus met?

What is this?

Tell us about your Experience with Metformin Hydrochloride; Pioglitazone Hydrochloride

Thank you for sharing your experience with us!

Share Your Experience

Druginformer Identified Side Effects: Diarrhoea, Feeling of despair, Decreased appetite

Posted By Anonymous in fdb.rxlist.com on May 30, 2015 @ 12:00 am

This medication increased my appetite, gave me diarrhea and made me feel horrible!

Druginformer Identified Side Effects: Pain, Depression, Diarrhoea, Feeling of despair, Gastrointestinal disorder, Weight decreased, Weight increased

Posted By Sue in fdb.rxlist.com on October 12, 2013 @ 12:00 am

Horrible! Gained 45 lbs, had trouble with pain with liver, did not control my A1c. Felt miserable constantly, digestive problems with diarrhea all the time. Went off of the med and lost weight and f...

Druginformer Identified Side Effects: None

Posted By Anonymous in fdb.rxlist.com on May 30, 2013 @ 12:00 am

Haven't had any problems with this med so fa

Druginformer Identified Side Effects: Dyspnoea, Swelling, Urinary tract infection, Weight increased

Posted By Anonymous in fdb.rxlist.com on February 10, 2013 @ 12:00 am

... met a few years. The side effects were Leg broke, Swelling of the lower leg or ankles,Weight gain (from 140 to 157 lbs), frequently Urinary tract infection and trouble breath. I stopped taking it afte...

Druginformer Identified Side Effects: None

Posted By actoplus in fdb.rxlist.com on September 10, 2011 @ 12:00 am

following doctors recomendation only

Druginformer Identified Side Effects: Oedema, Somnolence, Weight decreased, Weight increased

Posted By kjr in fdb.rxlist.com on August 24, 2011 @ 12:00 am

Did an adequate job of controlling my blood sugar, but started having other symtoms almost immediately. Weight gain, swollen feet and fatigue. Felt much better when I wasn't taking it, lost weight and...

Druginformer Identified Side Effects: Abnormal weight gain, Blood glucose, Angiogram, Aggression, Cardiac failure congestive

Posted By Marmot1 in fdb.rxlist.com on August 9, 2011 @ 12:00 am

This was a terrible drug and I regret allowing my Dr. to switch me from Metformin (which worked extremely well for me)to ActoplusMet 15/500. 1.)It did NOT control my blood sugar nearly as well as M...

Druginformer Identified Side Effects: None

Posted By Anonymous in fdb.rxlist.com on October 26, 2010 @ 12:00 am

Druginformer Identified Side Effects: Pain, Feeling jittery, Gait disturbance

Posted By Hurting in fdb.rxlist.com on October 20, 2010 @ 12:00 am

... my sugar down, my hemoglobin is now normal at 5.6. I have been walking a couple of miles everyday but for the last 2 3 weeks my joints, especially my hips are hurting a lot. That's effecting my mobili...

Druginformer Identified Side Effects: Diarrhoea, Dyspepsia

Posted By gtag75@aol.com in fdb.rxlist.com on September 14, 2010 @ 12:00 am

Has controled symtoms and A1c levels are good. i have encountered an upset stomach and diarrhea at times. I have been using this medication for over 1 year.


Additional Drug Information


* Warning: The facts and figures contained in these reports are accurate to the best of our capability; however, our metrics are only meant to augment your medical knowledge, and should never be used as the sole basis for selecting a new medication. As with any medical decision, be sure to work with your doctor to ensure the best choices are made for your condition.

* About FAERS: The FDA Adverse Event Reporting System (FAERS) is used by FDA for activities such as looking for new safety concerns that might be related to a marketed product, evaluating a manufacturer's compliance to reporting regulations and responding to outside requests for information. Reporting of adverse events is a voluntary process, and not every report is sent to FDA and entered into FAERS. The FAERS database may contain duplicate reports, the report quality is variable, and many factors may influence reporting (e.g., media attention, length of time a drug is marketed, market share). For these reasons, FAERS case reports cannot be used to calculate incidence or estimates of risk for a particular product or compare risks between products.