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Hydrochlorothiazide; Spironolactone

Popular Brands: : Aldactazide, Spironolactone And Hydrochlorothiazide, Spironolactone W/ Hydrochlorothiazide, Hydrochlorothiazide; Spironolactone
Official FDA Reports3,851
Social Media Events4
Total Posts114
Avg. Review Score4.50/ 5
Active Ingredients
  • Hydrochlorothiazide; Spironolactone
Manufacturers
  • Gd Searle Llc
  • Lederle Laboratories Div American Cyanamid Co
  • Mutual Pharmaceutical Co Inc

  This report is for all products sharing this active ingredient. For more details, please use our Workbench for research on individual brands like Aldactazide.

* Extracted from FDA Adverse Event Report

Explanation

The quarterly trend chart illustrates changing levels of adverse events over time. Results from both the FDA Adverse Event Database (FAERS) and adverse events extracted from social media by Druginformer are plotted side-by-side for easy comparison.


The proportion of people completing user reviews who complained about a side effect.

The proportion of social media adverse event complaints for each adverse event type.

The proportion of FAERS (FDA) adverse event complaints for each adverse event type.


Hydrochlorothiazide; Spironolactone Side Effects

  Social Media
(Online Comments)
FAERS
(Reports Submitted to FDA)
Side Effect On Drug
Label
Overall
Alarm
Reports % of
Reports
Alarm Reports % of
Reports
Alarm

* DrugInformer calculates alarm using a proprietary algorithm. Alarm should not be taken as an ofiicial signal from the FDA or other regulatory entity.


User Voices

The following are comments from users that experienced side effects while taking Hydrochlorothiazide; Spironolactone

Weight Decreased

My BP went from 180/110 to 136/78 and lost 10 pounds of water weight in 3 weeks


Source: comments/hydrochlorothiazide-spironola...

View full report on Hydrochlorothiazide; Spironolactone related weight decreased

Did the author experience weight decreased while taking aldactazide?

What is this?

Polyuria

Side Effects: None observed. No apparent increase in urination .

Works best as an additional med for hypertension but for me, not alone,


Source: ALDACTAZIDE: Side effects, ratings, an...

View full report on Hydrochlorothiazide; Spironolactone related polyuria

Did the author experience polyuria while taking aldactazide?

What is this?

Major Depression

I have Bi-polar disorder and Major Depressive Disorder - Spironolactone does not appear to be a good thing for me.


Source: Triamterene Hctz 37 5 25 Is This Drug ...

View full report on Hydrochlorothiazide; Spironolactone related major depression

Did the author experience major depression while taking hydrochlorothiazide; spironolactone?

What is this?

Tell us about your Experience with Hydrochlorothiazide; Spironolactone

Thank you for sharing your experience with us!

Share Your Experience

Druginformer Identified Side Effects: None

Posted By arl629@aol.com in fdb.rxlist.com on January 20, 2011 @ 12:00 am

still in the evaluation stage watching for side affects

Druginformer Identified Side Effects: None

Posted By Anonymous in askapatient.com on May 21, 2010 @ 12:00 am

Side Effects: None Dr. had me on Lisinopril (30 mg per day) for years and it did very little to lower my BP. When used in combo with Aldactazide, it was like flipping a switch.

Druginformer Identified Side Effects: None

Posted By Company13 in fdb.rxlist.com on July 7, 2009 @ 12:00 am

The tablets are slightly large, but go down easy.

Druginformer Identified Side Effects: None

Posted By Anonymous in drugs.com on September 25, 2008 @ 12:00 am

Mostly prescribed for high blood pressure, but I use it for pedal edema. It works great and it does have two diuretics in it which makes it better than just one diuretic.

Druginformer Identified Side Effects: Weight decreased

Posted By Anonymous in drugs.com on July 6, 2008 @ 12:00 am

My BP went from 180/110 to 136/78 and lost 10 pounds of water weight in 3 weeks

Druginformer Identified Side Effects: Polyuria

Posted By Anonymous in askapatient.com on April 9, 2005 @ 12:00 am

Side Effects: None observed. No apparent increase in urination. Works best as an additional med for hypertension but for me, not alone,

Druginformer Identified Side Effects: None

Posted By Anonymous in askapatient.com on March 3, 2003 @ 12:00 am

Not only the only effective drug, but also minimun side effects! No sexual side effects. I could write a book on the Doctors I've gone through and the combinations of dru...

Druginformer Identified Side Effects: None

Posted By almost medfree in healingwell.com on May 27, 2015 @ 12:00 am

I've been told I have sjogrens which is the cause of my dry eyes along with my fibro. I eye doctors recommended I switch to an eye drop with no preservatives. She specifically recommended the counter ...

Druginformer Identified Side Effects: None

Posted By SignaturePink in healingwell.com on May 25, 2015 @ 12:00 am

My eyes arent outwardly irritated but i do get sunken eyes or eyes that look sick. Usually on my worst days. I also have sore eyeballs. Does this happen to you, also?

Druginformer Identified Side Effects: None

Posted By LupusAndMe in facebook.com on May 23, 2015 @ 12:00 am

May 23 at 7:37am · Lupus and MeImmunosuppressant Medications Used In Lupus Azathioprine (Imuran) Mycophenolate mofetil (Cellcept) Cyclosporine (Neoral, Sandimmune, Gengraf) Methotrexate (Rheu...


Additional Drug Information


* Warning: The facts and figures contained in these reports are accurate to the best of our capability; however, our metrics are only meant to augment your medical knowledge, and should never be used as the sole basis for selecting a new medication. As with any medical decision, be sure to work with your doctor to ensure the best choices are made for your condition.

* About FAERS: The FDA Adverse Event Reporting System (FAERS) is used by FDA for activities such as looking for new safety concerns that might be related to a marketed product, evaluating a manufacturer's compliance to reporting regulations and responding to outside requests for information. Reporting of adverse events is a voluntary process, and not every report is sent to FDA and entered into FAERS. The FAERS database may contain duplicate reports, the report quality is variable, and many factors may influence reporting (e.g., media attention, length of time a drug is marketed, market share). For these reasons, FAERS case reports cannot be used to calculate incidence or estimates of risk for a particular product or compare risks between products.