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Popular Brands: : Spironolactone, Aldactone, Aldactone A, Verospiron, Spironol
Official FDA Reports189,128
Social Media Events998
Total Posts1,309
Avg. Review Score3.70/ 5

  This report is for all products sharing this active ingredient. For more details, please use our Workbench for research on individual brands like Spironolactone.

* Extracted from FDA Adverse Event Report


The quarterly trend chart illustrates changing levels of adverse events over time. Results from both the FDA Adverse Event Database (FAERS) and adverse events extracted from social media by Druginformer are plotted side-by-side for easy comparison.

The proportion of people completing user reviews who complained about a side effect.

The proportion of social media adverse event complaints for each adverse event type.

The proportion of FAERS (FDA) adverse event complaints for each adverse event type.

Spironolactone Side Effects

  Social Media
(Online Comments)
(Reports Submitted to FDA)
Side Effect On Drug
Reports % of
Alarm Reports % of

* DrugInformer calculates alarm using a proprietary algorithm. Alarm should not be taken as an ofiicial signal from the FDA or other regulatory entity.

User Voices

The following are comments from users that experienced side effects while taking Spironolactone


Side Effects: I noticed thinning of my hair . This is the only reason I stopped taking the drug, because my hair is naturally very fine iin texture and the thinning was more noticable than if my hair ...

Source: Aldactone (Spironolactone)

View full report on Spironolactone related alopecia

Did the author experience alopecia while taking spironolactone?

What is this?

Libido Increased

... My skin looked hydrated, clarity was good and the improvement was constant with no variations after the first 3 months. Also contributed a significant improvement to my libido . I am happy to co...

Source: Aldactone (Spironolactone)

View full report on Spironolactone related libido increased

Did the author experience libido increased while taking spironolactone?

What is this?

Breast Cancer

... every 14 days. After 12 months of use, DCIS detected in my right breast. No history of breast cancer in the family at all, and I was in good health otherwise. Malignant tumour of the breast was one of...

Source: Aldactone (Spironolactone)

View full report on Spironolactone related breast cancer

Did the author experience breast cancer while taking spironolactone?

What is this?

Tell us about your Experience with Spironolactone

Thank you for sharing your experience with us!

Share Your Experience

Druginformer Identified Side Effects: None

Effectiveness Rating:     Overall Rating:

Posted By Gigi on November 11, 2019 @ 8:43 am

eware!!!! This drug ruined my skin!!! I was on this drug for two weeks when I noticed aging around my eyes. I began to look tired as my skin began to sag & my eyelids began to droop. Later I started to notice other side effects. My hair began to thin around my forehead. My eyes became very dry, along with dry mouth & other mucous membranes. My skin felt thin under my arms & inner thighs, my skin still looks crepey. Once I realized it was the medication I had been on it for three months. I did not have a normal period for five months. I recently went to see my obgyn to discuss family planning. My fsh levels were abnormal for my age. I'm convinced this "hormone altering" drug is to blame for my recent side effects. I wish I had never touched this drug! I have seen no changes since I discontinued this drug eight months ago. I was aging so gracefully & this medication robbed me of that & possibly my chance of getting pregnant! If I can give any advice at all, DO NOT use this drug!!!

Druginformer Identified Side Effects: Somnolence

Effectiveness Rating:     Overall Rating:

Posted By diana on June 21, 2018 @ 3:23 am

after 1 25 mg table

Druginformer Identified Side Effects: Female sexual dysfunction

Posted By Anonymous in askapatient.com on September 18, 2015 @ 12:00 am

... 24-7 upon waking up. I tried to alter my diet, but nothing helped. I continued to have stomach issues, but my skin still looked amazing. By month 11 I started noticing sexual problems, I was diagnosed...

Druginformer Identified Side Effects: Headache, Polyuria, Dizziness, Abdominal distension, Amnesia, Insomnia, Muscular weakness, Somnolence, Swelling, Weight increased, Musculoskeletal discomfort, Pco2

Posted By Anonymous in askapatient.com on September 11, 2015 @ 12:00 am

... insomnia, muscle aches, and the worst one is the eyelid swelling. My left eyelid swells up to the point that it looks as though I've been punched in the face. I get daily headaches and feel like the ...

Druginformer Identified Side Effects: Anxiety, Depression, Mood altered, Emotional distress, Haemorrhage, Menstruation irregular

Posted By Anonymous in askapatient.com on September 9, 2015 @ 12:00 am

my hormonal acne cleared up (cheeks/jaw) but acne on forehead got worse due to anxiety/stress/depression-- which i think was because of the spiro--it made me very moody. Ruined my period...

Druginformer Identified Side Effects: Flatulence, Muscular weakness

Posted By Anonymous in askapatient.com on September 9, 2015 @ 12:00 am

Side Effects: Loss of water n salt from the body bcz of which bp was low..though results were v gud for my skin n jaw line..felt v weak and also suffered frm severe gas bcz of which i had breathing p...

Druginformer Identified Side Effects: Dizziness, Dry skin, Thirst, Hair growth abnormal, Irritability

Posted By Anonymous in askapatient.com on August 10, 2015 @ 12:00 am

Side Effects: Thirst, dizziness, dry skin, droopy eye lids, fine lines, irritability. In one month hair growth slowed down, don't really need to shave at all. I thought this drug was a mira...

Druginformer Identified Side Effects: Weight increased, Fatigue, Dizziness, Abdominal distension, Disturbance in attention, Muscle spasms, Rash

Posted By Anonymous in askapatient.com on July 23, 2015 @ 12:00 am

Side Effects: Tired , bloating , weight gain , dizzy , muscle cramping , foggy brain , not making sense when talking sometimes , and a rash all over my body

Druginformer Identified Side Effects: Breast pain, Loss of libido

Posted By Anonymous in askapatient.com on July 17, 2015 @ 12:00 am


Druginformer Identified Side Effects: Feeling cold, Hypoaesthesia, Feeling abnormal, Dyspnoea, Heart rate irregular, Muscular weakness, Paraesthesia

Posted By Anonymous in askapatient.com on July 12, 2015 @ 12:00 am

... this med I started feeling this horrible feeling in my chest and overall just not good feeling. At one point my legs and arms were tingly and my left hand became numb and cold to the touch, trouble b...

Additional Drug Information

* Warning: The facts and figures contained in these reports are accurate to the best of our capability; however, our metrics are only meant to augment your medical knowledge, and should never be used as the sole basis for selecting a new medication. As with any medical decision, be sure to work with your doctor to ensure the best choices are made for your condition.

* About FAERS: The FDA Adverse Event Reporting System (FAERS) is used by FDA for activities such as looking for new safety concerns that might be related to a marketed product, evaluating a manufacturer's compliance to reporting regulations and responding to outside requests for information. Reporting of adverse events is a voluntary process, and not every report is sent to FDA and entered into FAERS. The FAERS database may contain duplicate reports, the report quality is variable, and many factors may influence reporting (e.g., media attention, length of time a drug is marketed, market share). For these reasons, FAERS case reports cannot be used to calculate incidence or estimates of risk for a particular product or compare risks between products.