DrugInformer Search

Estradiol; Norethindrone Acetate

Popular Brands: : Activella, Combipatch, Estradiol And Norethindrone Acetate, Mimvey, Estradiol / Norethindrone Acetate
Official FDA Reports6,457
Social Media Events379
Total Posts277
Avg. Review Score3.65/ 5
Active Ingredients
  • Estradiol; Norethindrone Acetate
Manufacturers
  • Amneal Pharmaceuticals Llc
  • Breckenridge Pharmaceutical Inc
  • Breckenridge Pharmaceutical, Inc.
  • Noven Pharmaceuticals Inc
  • Teva Pharmaceuticals Usa Inc

  This report is for all products sharing this active ingredient. For more details, please use our Workbench for research on individual brands like Activella.

* Extracted from FDA Adverse Event Report

Explanation

The quarterly trend chart illustrates changing levels of adverse events over time. Results from both the FDA Adverse Event Database (FAERS) and adverse events extracted from social media by Druginformer are plotted side-by-side for easy comparison.


The proportion of people completing user reviews who complained about a side effect.

The proportion of social media adverse event complaints for each adverse event type.

The proportion of FAERS (FDA) adverse event complaints for each adverse event type.


Estradiol; Norethindrone Acetate Side Effects

  Social Media
(Online Comments)
FAERS
(Reports Submitted to FDA)
Side Effect On Drug
Label
Overall
Alarm
Reports % of
Reports
Alarm Reports % of
Reports
Alarm

* DrugInformer calculates alarm using a proprietary algorithm. Alarm should not be taken as an ofiicial signal from the FDA or other regulatory entity.


User Voices

The following are comments from users that experienced side effects while taking Estradiol; Norethindrone Acetate

Thrombosis

The package insert warns of serious side effects such as breast cancer, cancer of the uterus, stroke, heart attack, blood clots and dementia. I had been one determined to go through meno...


Source: Combipatch

View full report on Estradiol; Norethindrone Acetate related thrombosis

Did the author experience thrombosis while taking combipatch?

What is this?

Cerebrovascular Accident

The package insert warns of serious side effects such as breast cancer, cancer of the uterus, stroke , heart attack, blood clots and dementia. I had been one determined to go through meno...


Source: Combipatch

View full report on Estradiol; Norethindrone Acetate related cerebrovascular accident

Did the author experience cerebrovascular accident while taking combipatch?

What is this?

Myocardial Infarction

The package insert warns of serious side effects such as breast cancer, cancer of the uterus, stroke, heart attack , blood clots and dementia. I had been one determined to go through meno...


Source: Combipatch

View full report on Estradiol; Norethindrone Acetate related myocardial infarction

Did the author experience myocardial infarction while taking combipatch?

What is this?

Tell us about your Experience with Estradiol; Norethindrone Acetate

Thank you for sharing your experience with us!

Share Your Experience

Druginformer Identified Side Effects: Flatulence, Dry skin

Posted By Anonymous in askapatient.com on September 8, 2015 @ 12:00 am

Side Effects: Side effects??? I would have welcomed them! the patch was coming off within 2 hours! And my skin is as dry as a popcorn fart. Why not just make them like the tagederm Patc...

Druginformer Identified Side Effects: Alopecia, Anxiety, Premenstrual syndrome, Acne, Insomnia

Posted By Anonymous in askapatient.com on August 24, 2015 @ 12:00 am

Side Effects: increased anxiety, hair loss, acne, insomnia, pms type feelings all month long The progestin in this (norethindrone acetate) is very androgenic. For me, this patch increased m...

Druginformer Identified Side Effects: Coagulopathy, Drug ineffective, Muscle spasms, Haemorrhage

Posted By Llipa in fdb.rxlist.com on July 25, 2015 @ 12:00 am

... seemed a great alternative. The side affects were not tolerable and it did nothing for libido or sleep. Hot flashes improved but had been mild. Started heavy bleeding, clotting right away. Called the ...

Druginformer Identified Side Effects: Vulvovaginal dryness, Alopecia, Weight increased

Posted By Anonymous in askapatient.com on June 16, 2015 @ 12:00 am

Side Effects: Significant hair thinning. Weight gain in abdomen, hip, + thighs. The patch improved my sex life significantly. I just had tummy tuck, and have been working out to improve my ...

Druginformer Identified Side Effects: Menstruation irregular

Posted By Anonymous in askapatient.com on May 7, 2015 @ 12:00 am

Side Effects: The first couple months I spotted lightly a few times but then that was it, it went away. I do have a red mark when I change patches but that goes away after a day or so, NO site itchin...

Druginformer Identified Side Effects: Thrombosis

Posted By Anonymous in askapatient.com on May 6, 2015 @ 12:00 am

Side Effects: I developed a blood clot (DVT) in my right leg and my left arm. Thank God it was caught in time before any serious health issues. This product is good but caused a blood clot ...

Druginformer Identified Side Effects: Thrombosis

Posted By Spencer in fdb.rxlist.com on May 6, 2015 @ 12:00 am

This medication resulted in a blood clot (DVT) in my right leg and left arm. It was caught in time and treated with Lovenox and Coumadin.

Druginformer Identified Side Effects: Breast tenderness, Insomnia, Muscle spasms, Haemorrhage, Menstruation irregular

Posted By Waw in fdb.rxlist.com on April 23, 2015 @ 12:00 am

I had almost immediate releif from hot flashes and insomnia, but after 4 weeks on the combi patch I started spotting/ bleeding, cramps and tender breasts. Now GYN wants to do a Endometrial biopsy...it...

Druginformer Identified Side Effects: Menstruation irregular

Posted By Anonymous in askapatient.com on April 1, 2015 @ 12:00 am

Side Effects: occasional spotting the first 6 months then it stopped.. No other side effects. I feel GREAT! This has been a miracle for me. I tried other hormone therapy and even the sup...

Druginformer Identified Side Effects: Somnolence, Weight increased, Haemorrhage

Posted By Anonymous in fdb.rxlist.com on March 18, 2015 @ 12:00 am

I am 53 and perimenopausal. I was looking for treatment for hot flashes, mood swings and fatigue. The patch worked to treat those symptoms pretty much immediately - what a relief! Unfortunately my pr...


Additional Drug Information


* Warning: The facts and figures contained in these reports are accurate to the best of our capability; however, our metrics are only meant to augment your medical knowledge, and should never be used as the sole basis for selecting a new medication. As with any medical decision, be sure to work with your doctor to ensure the best choices are made for your condition.

* About FAERS: The FDA Adverse Event Reporting System (FAERS) is used by FDA for activities such as looking for new safety concerns that might be related to a marketed product, evaluating a manufacturer's compliance to reporting regulations and responding to outside requests for information. Reporting of adverse events is a voluntary process, and not every report is sent to FDA and entered into FAERS. The FAERS database may contain duplicate reports, the report quality is variable, and many factors may influence reporting (e.g., media attention, length of time a drug is marketed, market share). For these reasons, FAERS case reports cannot be used to calculate incidence or estimates of risk for a particular product or compare risks between products.