This report is for all products sharing this active ingredient. For more details, please use our Workbench for research on individual brands like Estradiol.
The quarterly trend chart illustrates changing levels of adverse events over time. Results from both the FDA Adverse Event Database (FAERS) and adverse events extracted from social media by Druginformer are plotted side-by-side for easy comparison.
The proportion of people completing user reviews who complained about a side effect.
The proportion of social media adverse event complaints for each adverse event type.
The proportion of FAERS (FDA) adverse event complaints for each adverse event type.
Social Media (Online Comments) |
FAERS (Reports Submitted to FDA) |
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Side Effect | On Drug Label |
Overall Alarm |
Reports | % of Reports |
Alarm | Reports | % of Reports |
Alarm |
* DrugInformer calculates alarm using a proprietary algorithm. Alarm should not be taken as an ofiicial signal from the FDA or other regulatory entity.
Druginformer Identified Side Effects: Vulvovaginal dryness, Discomfort
Posted By 2maui in fdb.rxlist.com on October 9, 2015 @ 12:00 am
“... Even my doctor said she couldn't get it to go in as far as directed! It almost stuck out! She suggested using a tampon to help it stay in place. What???? I have vaginal dryness due to menopause. Why w...”
Druginformer Identified Side Effects: None
Posted By Tsarina in fdb.rxlist.com on September 28, 2015 @ 12:00 am
“I've been on this med since 1995. I got hot flashes every hour lasting 15 minutes. Yes, I'm 70 and still get them if I don't stay on this. My rx doesn't cover so I've tried pills. They work but make m...”
Druginformer Identified Side Effects: None
Posted By jilly54 in fdb.rxlist.com on September 21, 2015 @ 12:00 am
“This medicine has gave me a pulmonary embolism. PLEASE DON'T USE”
Druginformer Identified Side Effects: None
Posted By Anonymous in askapatient.com on September 9, 2015 @ 12:00 am
“Side Effects: None I started Vagifem 25 mcg, and it has been great. when reducing it to 10 mcg a few months ago, I have now started to be a bit itchy again, so I am wondering if I could tak...”
Druginformer Identified Side Effects: Fatigue, Photopsia
Posted By Anonymous in askapatient.com on September 6, 2015 @ 12:00 am
“Side Effects: A bit tired initially. .but wonderful next day. I take alternately. Every second day. No more flashes ..and feeling normal.again ”
Druginformer Identified Side Effects: Pain, Chills, Vomiting, Anxiety, Diarrhoea, Somnolence
Posted By Anonymous in askapatient.com on September 2, 2015 @ 12:00 am
“Side Effects: Horrendous diarrhoea and vomiting,shivering, aching,tiredness and general feelings of anxiety I had a full hysterectomy 10 years ago and was never given HRT but after a visit ...”
Druginformer Identified Side Effects: Muscle spasms
Posted By Anonymous in askapatient.com on August 28, 2015 @ 12:00 am
“Side Effects: Seems to be working well, however took about 9 weeks. Some light cramping but tolerable. I've tried everything over the past 2 years and this is working. I would recommend t...”
Druginformer Identified Side Effects: Weight increased, Breast tenderness, Headache
Posted By Anonymous in askapatient.com on August 24, 2015 @ 12:00 am
“Side Effects: Breast tenderness, headaches & Weight gain. ”
Druginformer Identified Side Effects: Alopecia
Posted By Anonymous in askapatient.com on August 23, 2015 @ 12:00 am
“Side Effects: Hair loss.....too much. My doctor told me to stop immediately before I become bald. ”
Druginformer Identified Side Effects: Pain, Dementia, Accidental poisoning, Muscle spasms, Vulvovaginal pruritus
Posted By Anonymous in askapatient.com on August 22, 2015 @ 12:00 am
“... will be getting a pelvic and transvaginal ultrasound just to make sure all is okay since I was diagnosed with stage 2 breast cancer 2 years ago. She wants to make sure the pain is not from anything el...”
* Warning: The facts and figures contained in these reports are accurate to the best of our capability; however, our metrics are only meant to augment your medical knowledge, and should never be used as the sole basis for selecting a new medication. As with any medical decision, be sure to work with your doctor to ensure the best choices are made for your condition.
* About FAERS: The FDA Adverse Event Reporting System (FAERS) is used by FDA for activities such as looking for new safety concerns that might be related to a marketed product, evaluating a manufacturer's compliance to reporting regulations and responding to outside requests for information. Reporting of adverse events is a voluntary process, and not every report is sent to FDA and entered into FAERS. The FAERS database may contain duplicate reports, the report quality is variable, and many factors may influence reporting (e.g., media attention, length of time a drug is marketed, market share). For these reasons, FAERS case reports cannot be used to calculate incidence or estimates of risk for a particular product or compare risks between products.
User Voices
The following are comments from users that experienced side effects while taking Estradiol
Breast Tenderness
“Didn't see much of a change but did make my breasts sore ”
Source: Estradiol
View full report on Estradiol related breast tenderness
Did the author experience breast tenderness while taking estradiol?
What is this?Drug Ineffective
“Didn't help me at all.”
Source: Estradiol
View full report on Estradiol related drug ineffective
Did the author experience drug ineffective while taking estradiol?
What is this?Sleep Disorder
“had so many symptoms now mostly under control, experienced hair loss, acne, anxiety, sadness, panic attacks, sleepless nights and the list goes on. Mirena coil and low dose premarin 0.3 seems to be th...”
Source: Estradiol
View full report on Estradiol related sleep disorder
Did the author experience sleep disorder while taking estradiol?
What is this?