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Lisdexamfetamine Dimesylate

Popular Brands: : Vyvanse, Lisdexamfetamine Dimesylate
Official FDA Reports22,889
Social Media Events5,097
Total Posts5,018
Avg. Review Score3.72/ 5
Active Ingredients
  • Lisdexamfetamine Dimesylate
Brands and Other Names
  • Shire Development Inc

  This report is for all products sharing this active ingredient. For more details, please use our Workbench for research on individual brands like Vyvanse.

* Extracted from FDA Adverse Event Report


The quarterly trend chart illustrates changing levels of adverse events over time. Results from both the FDA Adverse Event Database (FAERS) and adverse events extracted from social media by Druginformer are plotted side-by-side for easy comparison.

The proportion of people completing user reviews who complained about a side effect.

The proportion of social media adverse event complaints for each adverse event type.

The proportion of FAERS (FDA) adverse event complaints for each adverse event type.

Lisdexamfetamine Dimesylate Side Effects

  Social Media
(Online Comments)
(Reports Submitted to FDA)
Side Effect On Drug
Reports % of
Alarm Reports % of

* DrugInformer calculates alarm using a proprietary algorithm. Alarm should not be taken as an ofiicial signal from the FDA or other regulatory entity.

User Voices

The following are comments from users that experienced side effects while taking Lisdexamfetamine Dimesylate

Increased Appetite

Soo I've taken my Vyvanse but yet I am still feeling hungry . That is extreme @fatgirlproblems!

Source: KrystalLCollins/statuses/1947990783270...

View full report on Lisdexamfetamine Dimesylate related increased appetite

Did the author experience increased appetite while taking vyvanse?

What is this?


Fuck you vyvanse. My bodies tired, but your bitchass is keeping me up

Source: Matt_welch/statuses/193231379276890114

View full report on Lisdexamfetamine Dimesylate related insomnia

Did the author experience insomnia while taking lisdexamfetamine dimesylate?

What is this?

Dry Mouth

... unless you really need it, Vyvanse has been nothing but perfect for me. My doctor put me on it a few weeks ago and so far, the worst side effect I have noticed was occasional dry mouth , and that was ...

Source: Vyvanse-Capsules-review-17d02

View full report on Lisdexamfetamine Dimesylate related dry mouth

Did the author experience dry mouth while taking vyvanse?

What is this?

Tell us about your Experience with Lisdexamfetamine Dimesylate

Thank you for sharing your experience with us!

Share Your Experience

Druginformer Identified Side Effects: Oedema peripheral, Arthralgia

Effectiveness Rating:     Overall Rating:

Posted By Matthew on August 10, 2018 @ 5:44 pm

Found not very effective in from about 4-5 tops. Legs started swelling calves shins to ankles after few days. Gradually got worse. It was though from something else had dosage change from 30-50. Had full heart check echo cardio gram ECG Regular BP, which all showed fine. Compared to when using normal Dexamfetamine I found nothing but problems with the one a day dosage. Legs not improved, so speaking to Psychiatrist and going back to normal Dexamfetamine twice daily where no Edema of the legs occurred at all.

Druginformer Identified Side Effects: Dry mouth, Insomnia

Effectiveness Rating:     Overall Rating:

Posted By Jessica on February 15, 2018 @ 9:09 pm

Works well, but never lasts long enough for me

Druginformer Identified Side Effects: None

Effectiveness Rating:     Overall Rating:

Posted By Martine on April 20, 2016 @ 2:45 am

Since I've upgraded my dose of vyvanse to 30 mg in the morning and 10 mg in the afternoon, I've experienced ocular discomforts that manifest into eyelids twitching left and right, upper eyelids muscular pressure, eye dryness and potentially prone to conjontivitis

Druginformer Identified Side Effects: Back pain, Paranoia, Schizophrenia, Neurotoxicity, Parkinson's disease

Posted By Anonymous in askapatient.com on September 13, 2015 @ 12:00 am

... inducing permanent brain changes reminiscent of paranoid schizophrenia in animal models. Giving dexamfetamine for as little as three weeks to monkeys, rats and all other species tested causes a 50-80%...

Druginformer Identified Side Effects: Headache, Sleep disorder, Dehydration, Weight decreased

Posted By Anonymous in askapatient.com on September 5, 2015 @ 12:00 am

Side Effects: weight loss, sleep disturbances, dehydration, headaches I think this drug is very smooth and I can focus and stay on task..if I CHOOSE to. If i allow myself to 'follow' all my...

Druginformer Identified Side Effects: Weight decreased, Memory impairment, Decreased appetite

Posted By Anonymous in askapatient.com on August 19, 2015 @ 12:00 am

... a lot (e.g. Setting up my new classroom). At least this way I get some help without having side effects every day. I used to take vyvanse on a daily basis but lost a lot of weight in a short peri...

Druginformer Identified Side Effects: Fatigue

Posted By Anonymous in askapatient.com on August 16, 2015 @ 12:00 am

Side Effects: Not sure if I like this med, I take it at 7am and seems to wear off by 1pm. I'm exhausted when it wears off. My Dr said it lasts from 12-14 hrs, maybe my dose isn't high enough?

Druginformer Identified Side Effects: Anger, Dry eye, Dry mouth, Irritability, Decreased appetite

Posted By Anonymous in askapatient.com on August 2, 2015 @ 12:00 am

Side Effects: Dry mouth, dry eyes, small loss of appetite occasionally, a easier to irritate (I consider this less of a side effect, as I was impossible to get angry at anything, unless you messed wi...

Druginformer Identified Side Effects: Nausea, Diarrhoea, Insomnia, Decreased appetite

Posted By Anonymous in askapatient.com on August 1, 2015 @ 12:00 am

Side Effects: Diarrhea, sleep loss, loss of appetite, nausea. As I type this it is 4:30 am. I have just had my first day taking this. It worked wonders at work yesterday and I was just wor...

Druginformer Identified Side Effects: Adverse event, Heart rate, Confusional state, Depression, Dizziness, Palpitations, Dry mouth, Dysgeusia, Mental impairment, Ocular hyperaemia, Pyrexia, Weight increased

Posted By Anonymous in askapatient.com on July 24, 2015 @ 12:00 am

Side Effects: Dizziness everytime i stand up or walk around for too long, flashes of light in the side of my eyes later at night, very fast hard pounding heart rate, fever once, really red eyes, supe...

Additional Drug Information

* Warning: The facts and figures contained in these reports are accurate to the best of our capability; however, our metrics are only meant to augment your medical knowledge, and should never be used as the sole basis for selecting a new medication. As with any medical decision, be sure to work with your doctor to ensure the best choices are made for your condition.

* About FAERS: The FDA Adverse Event Reporting System (FAERS) is used by FDA for activities such as looking for new safety concerns that might be related to a marketed product, evaluating a manufacturer's compliance to reporting regulations and responding to outside requests for information. Reporting of adverse events is a voluntary process, and not every report is sent to FDA and entered into FAERS. The FAERS database may contain duplicate reports, the report quality is variable, and many factors may influence reporting (e.g., media attention, length of time a drug is marketed, market share). For these reasons, FAERS case reports cannot be used to calculate incidence or estimates of risk for a particular product or compare risks between products.