DrugInformer Search

Bupropion Hydrochloride Related Mania

Official FDA Reports294
Social Media Events121

  This report is for all products sharing this active ingredient. For more details, please use our Workbench for research on individual brands like Wellbutrin.


The quarterly trend chart illustrates changing levels of adverse events over time. Results from both the FDA Adverse Event Database (AERS) and adverse events extracted from social media by Druginformer are plotted side-by-side for easy comparison.

List of Possible Side Effects Reported

Report Date Dosage Indication Outcome Country Gender Age Weight (lbs)

* DrugInformer calculates alarm using a proprietary algorithm. Alarm should not be taken as an ofiicial signal from the FDA or other regulatory entity.

Social Media Comments From Around the Web

The following are comments from users that experienced side effects while taking Milnacipran Hydrochloride


It seems to be helping with my depression. Originally I did get the side affect of slight mania increased sex drive and some dizziness. I also did recently go through withdrawls when I had to wait a d...

Source:" Wellbutrin

View full report on drug related mania

Did the author experience mania while taking wellbutrin?

What is this?


caused manic episode

Source:" Wellbutrin

View full report on drug related mania

Did the author experience mania while taking wellbutrin?

What is this?


... medicine always made me feel weird, a lot of racing thoughts. I chalked it up to my depression dwendling away. When I was diagnosed with bipolar last year it all made sense, it was making me manic !...

Source:" Wellbutrin

View full report on drug related mania

Did the author experience mania while taking wellbutrin?

What is this?

Tell us about your Experience with Bupropion Hydrochloride Related Mania

Thank you for sharing your experience with us!

Share Your Experience

Druginformer Identified Side Effects: Tremor, Drug withdrawal syndrome, Adverse event, Cardiac flutter, Insomnia, Irritability, Mania, Pain in extremity, Restlessness, Speech disorder

Posted By Anonymous in askapatient.com on April 12, 2015 @ 12:00 am

Side Effects: Mania, terrible withdrawal Worked great at first, then started feeling manic/anxious/irritable. Was talking really fast and interrupting people and not getting much sleep. Dec...

Druginformer Identified Side Effects: Insomnia, Mania

Posted By Anonymous in drugs.com on February 17, 2014 @ 12:00 am

... a day, but I think I need to just take it in the morning. I don't feel all energetic but I haven't been taking a nap in the afternoon like usual. And tonight I can't fall asleep...and I take 100mg of ...

Druginformer Identified Side Effects: Crying, Depression, Mania, Somnolence

Posted By Anonymous in askapatient.com on December 11, 2012 @ 12:00 am

Side Effects: It took 4 days to have enough in my system to stop crying all the time. May have to back down dose because it causes a little mania. I was told I shold take it in the morning but it mak...

Druginformer Identified Side Effects: Back pain, Tinnitus, Palpitations, Euphoric mood, Dry mouth, Hypertension, Insomnia, Mania, Urine abnormality, Appetite disorder

Posted By stressed out wonder in fdb.rxlist.com on April 21, 2012 @ 12:00 am

... and employees (I'm told more than usual), and develpoed palpitations, hypertension, ringing in the ears, dry mouth, frequent need to urinate, horrible neck, and upper back pain, and difficulty falling...

Druginformer Identified Side Effects: Constipation, Headache, Nausea, Tinnitus, Dysgeusia, Mania, Tenderness, Vision blurred, Decreased appetite, Energy increased

Posted By Anonymous in askapatient.com on January 20, 2012 @ 12:00 am

First few weeks: increased energy, decreased appetite, less need for sleep, horrible ringing in the ears, constipation, general mania. Past few months: headache, nausea, blurred vision,...

Druginformer Identified Side Effects: Pain, Anxiety, Obsessive-compulsive disorder, Restless legs syndrome, Amnesia, Electric shock, Insomnia, Mania, Restlessness

Posted By Anonymous in askapatient.com on October 28, 2011 @ 12:00 am

... to cook or clean or organise and still can not 8 yrs later. Had horrible reaction to going off. Electric shocks in head and body with every step I took and every movement. Painful shocks! Lost who I w...

Druginformer Identified Side Effects: Drug ineffective, Mania

Posted By Anonymous in askapatient.com on September 15, 2011 @ 12:00 am

Side Effects: rapid-cycling, mania I was prescribed Effexor XR on two separate occasions. Both times I almost immediately switched from depression into rapid-cycling and the second time thi...

Druginformer Identified Side Effects: Nausea, Drug withdrawal syndrome, Adverse event, Disturbance in sexual arousal, Abnormal dreams, Mania, Emotional distress

Posted By Anonymous in askapatient.com on July 20, 2011 @ 12:00 am

Side Effects: I later switched to Venlafaxine, a generic form of Effexor. The side effects have remained consistant. They include, daily nausea, unless taken with food. Mild sexual side effects, an...

Druginformer Identified Side Effects: Dizziness, Memory impairment, Cardiac flutter, Yawning, Abnormal dreams, Arrhythmia, Mania

Posted By Anonymous in askapatient.com on July 5, 2011 @ 12:00 am

Side Effects: In beginning: Constant yawning, racing heart, weird dreams, dizziness, mania; after a few weeks: NONE :) If I forget to take for a couple days, I do get heart palpitations and bad dizzi...

Druginformer Identified Side Effects: Irritability, Mania, Headache, Feeling abnormal, Insomnia

Posted By Anonymous in askapatient.com on May 4, 2011 @ 12:00 am

Side Effects: Spaced out feeling, headaches & sleeplessness. Feel irritable or manic! Was prescribed this approx 7 years ago & stopped completely on DAY 12 - for 11MONTHS. This time I hav...

* Warning: The facts and figures contained in these reports are accurate to the best of our capability; however, our metrics are only meant to augment your medical knowledge, and should never be used as the sole basis for selecting a new medication. As with any medical decision, be sure to work with your doctor to ensure the best choices are made for your condition.

* About FAERS: The FDA Adverse Event Reporting System (FAERS) is used by FDA for activities such as looking for new safety concerns that might be related to a marketed product, evaluating a manufacturer's compliance to reporting regulations and responding to outside requests for information. Reporting of adverse events is a voluntary process, and not every report is sent to FDA and entered into FAERS. The FAERS database may contain duplicate reports, the report quality is variable, and many factors may influence reporting (e.g., media attention, length of time a drug is marketed, market share). For these reasons, FAERS case reports cannot be used to calculate incidence or estimates of risk for a particular product or compare risks between products.