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Diphenhydramine Hydrochloride Related Irritability

Official FDA Reports208
Social Media Events41
Active Ingredients
  • Diphenhydramine Hydrochloride
Additional Drug Brands and Names
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Additional Terms for Irritability
  • Short Tempered
  • Irritated
  • Grouchy
  • Irratibility
  • Grumpy
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  This report is for all products sharing this active ingredient. For more details, please use our Workbench for research on individual brands like Benadryl.


Explanation

The quarterly trend chart illustrates changing levels of adverse events over time. Results from both the FDA Adverse Event Database (AERS) and adverse events extracted from social media by Druginformer are plotted side-by-side for easy comparison.


List of Possible Side Effects Reported

Report Date Dosage Indication Outcome Country Gender Age Weight (lbs)

* DrugInformer calculates alarm using a proprietary algorithm. Alarm should not be taken as an ofiicial signal from the FDA or other regulatory entity.


Social Media Comments From Around the Web

The following are comments from users that experienced side effects while taking Milnacipran Hydrochloride

Diphenhydramine Hydrochloride

... after the 3rd try and I have not gotten a minute of sleep. I took 2 capsules before bed and although it made me very sleepy, I've become restless all over my body. I feel irritable and horrible and ca...


Source:" drugs/drugreview-161075-ZzzQuil+oral.a...

View full report on drug related irritability

Did the author experience irritability while taking diphenhydramine hydrochloride?

What is this?

Benadryl

... bed. I dont recommend anybody to take it for a sleep aid. Only use for any type if allergic reactions. Also if I got it in a shot form from my Dr I would fill anxious and irritated . Not good

...


Source:" BENADRYL: Side effects, ratings, and p...

View full report on drug related irritability

Did the author experience irritability while taking benadryl?

What is this?

Benadryl

effects>Irritability Racing heart Anxiety Tremors Severe mood swings Paranoia Anger outbursts


Source:" BENADRYL: Side effects, ratings, and p...

View full report on drug related irritability

Did the author experience irritability while taking benadryl?

What is this?

Tell us about your Experience with Diphenhydramine Hydrochloride Related Irritability

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Share Your Experience

Druginformer Identified Side Effects: Hypersomnia, Irritability, Restlessness, Somnolence

Posted By IsabellaL in fdb.rxlist.com on September 30, 2014 @ 12:00 am

... 2 capsules and was out like a light in no time. I slept from 11pm to 3pm and felt like I was in a horrible haze all the next day. Second day took me a bit longer to fall asleep and was feeling a bit...

Druginformer Identified Side Effects: Loss of consciousness, Anxiety, Dyspnoea, Irritability, Muscle twitching

Posted By Anonymous in askapatient.com on September 12, 2014 @ 12:00 am

... like I was going to have an anxiety attack. While I would be laying in my arms and legs would start twitching then my whole body would twitch. I would twitch so bad I would almost fall out of bed. I d...

Druginformer Identified Side Effects: Tremor, Paranoia, Mood swings, Anger, Anxiety, Arrhythmia, Irritability, Mood altered

Posted By Anonymous in askapatient.com on June 4, 2014 @ 12:00 am

Irritability Racing heart Anxiety Tremors Severe mood swings Paranoia Anger outbursts

Druginformer Identified Side Effects: Hypersomnia, Akathisia, Irritability, Somnolence

Posted By S in fdb.rxlist.com on January 10, 2014 @ 12:00 am

Condition: Fall asleep easily,but wake for 2-3 hrs during night & RLS. I still wake during night, but no RLS. Go back to sleep easily and sleep another 4-5hrs. Groggy and irritable next morning.

Druginformer Identified Side Effects: Hypersomnia, Irritability, Restlessness

Posted By misskrissie in viewpoints.com on December 28, 2013 @ 12:00 am

... in fact I think this product may have also contributed to me feeling very restless and irritable rather than sleepy. I normally lay in bed for about half an hour before I fall asleep, but it took me f...

Druginformer Identified Side Effects: Feeling cold, Fatigue, Feeling jittery, Cardiac flutter, Dry eye, Irritability, Somnolence

Posted By Anonymous in askapatient.com on March 18, 2012 @ 12:00 am

... so so SO tired but everytime I lay down and close my eyes my heart races and I jump awake trying to catch my breath. Had same problem when given demorhal while in labour. Cold and jittery, dry eyes an...

Druginformer Identified Side Effects: Hallucination, Irritability, Muscle twitching, Somnolence

Posted By Anonymous in askapatient.com on March 17, 2012 @ 12:00 am

... if I take to much and extreme irritability .relaxation drowsiness. 2 pills to go directly to sleep , four to stay up and be relaxed .ive read that this drug causes hallucinations however I've never ta...

Druginformer Identified Side Effects: Cold sweat, Anger, Anxiety, Social fear, Irritability, Mood altered, Panic attack, Weight increased

Posted By Anonymous in askapatient.com on March 16, 2012 @ 12:00 am

... social anxiety and panic attacks.... But lost effectiveness. I would feel extremely anxious irritable moody and angry after taking too many days straight. I would wake up in a cold sweat. It also made...

Druginformer Identified Side Effects: Headache, Nausea, Anxiety, Restless legs syndrome, Cardiac flutter, Blood pressure increased, Irritability

Posted By Anonymous in askapatient.com on December 29, 2011 @ 12:00 am

Side Effects: Headache, nausea, irritability, anxiety, restless legs, increased heart rate and increased blood pressure.

Druginformer Identified Side Effects: Headache, Nervousness, Palpitations, Anxiety, Body temperature, Premenstrual syndrome, Irritability, Restlessness

Posted By Anonymous in askapatient.com on December 27, 2011 @ 12:00 am

Severe Anxiety Restlessness Extreme Irratibility Higher Heart Rate Sometimes a low body temperature Headaches Up and Down Mood I've gone through everything I've been taking (mos...



* Warning: The facts and figures contained in these reports are accurate to the best of our capability; however, our metrics are only meant to augment your medical knowledge, and should never be used as the sole basis for selecting a new medication. As with any medical decision, be sure to work with your doctor to ensure the best choices are made for your condition.

* About FAERS: The FDA Adverse Event Reporting System (FAERS) is used by FDA for activities such as looking for new safety concerns that might be related to a marketed product, evaluating a manufacturer's compliance to reporting regulations and responding to outside requests for information. Reporting of adverse events is a voluntary process, and not every report is sent to FDA and entered into FAERS. The FAERS database may contain duplicate reports, the report quality is variable, and many factors may influence reporting (e.g., media attention, length of time a drug is marketed, market share). For these reasons, FAERS case reports cannot be used to calculate incidence or estimates of risk for a particular product or compare risks between products.