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Gabapentin Related Irritability

Official FDA Reports529
Social Media Events48
Active Ingredients
  • Gabapentin
Additional Drug Brands and Names
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Additional Terms for Irritability
  • Short Tempered
  • Irritated
  • Grouchy
  • Irratibility
  • Grumpy
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  This report is for all products sharing this active ingredient. For more details, please use our Workbench for research on individual brands like Neurontin.


The quarterly trend chart illustrates changing levels of adverse events over time. Results from both the FDA Adverse Event Database (AERS) and adverse events extracted from social media by Druginformer are plotted side-by-side for easy comparison.

List of Possible Side Effects Reported

Report Date Dosage Indication Outcome Country Gender Age Weight (lbs)

* DrugInformer calculates alarm using a proprietary algorithm. Alarm should not be taken as an ofiicial signal from the FDA or other regulatory entity.

Social Media Comments From Around the Web

The following are comments from users that experienced side effects while taking Milnacipran Hydrochloride


Side Effects: Nausea, extreme sleepiness,severe headache, jittery, not myself,extremely grouchy , easily upset.

None Day one I felt negative side effects after taking the second...

Source:" Neurontin (Gabapentin)

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Side Effects: Constant and severe drowiness; irritability to the max, actually wanted to kill someone, anyone; blurred vision; headaches; sinus pressure; walking imbalance; increased appetite; diffic...

Source:" Neurontin (Gabapentin)

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... and no more sugar cravings. Unfortunately after 6 months at 600mg, I've had to lower the dose back to 300mg because I've developed mild, but unwanted side effects like irritability , anxiety and weird ...

Source:" Gabapentin Oral : User Ratings coverin...

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Druginformer Identified Side Effects: Pain, Hypoaesthesia, Anxiety, Food craving, Feelings of worthlessness, Irritability, Paraesthesia, Somnolence, Intervertebral disc degeneration

Posted By jljhome in fdb.rxlist.com on August 13, 2014 @ 12:00 am

... self-doubt, definitely not my normal personality. My doctor also added 10mg of Amitriptylin back into the mix to hopefully offset any remaining side effects and possible increase in pain at the lower ...

Druginformer Identified Side Effects: Aggression, Irritability

Posted By Anonymous in drugs.com on January 4, 2014 @ 12:00 am

... does tend to wear off a little near the time of the next dosage. Ramping up to a high dosage so quickly definitely made me feel a bit tripy, as well as paranoid, irritable and aggressive but this has,...

Druginformer Identified Side Effects: Fatigue, Irritability

Posted By gabapentin: In August 2012 my ... in drugs.com on January 18, 2013 @ 12:00 am

... early Dec. and he ordered Gabapentin, starting at 1 pill and then increasing weekly up to 4 pills. It's mid January and I am still only taking 2 pills because I am always tired and a little nauseated....

Druginformer Identified Side Effects: Dizziness, Pruritus, Disorientation, Hypertension, Irritability, Mental impairment

Posted By Anonymous in askapatient.com on December 19, 2012 @ 12:00 am

Side Effects: Disorientation, dizziness, high blood pressure, itching hands & ankles, inabilty to get out the right word, some irritability, unable to focus & stay on task This med helped w...

Druginformer Identified Side Effects: Hypersomnia, Dizziness, Feeling intoxicated, Disturbance in attention, Irritability, Somnolence

Posted By Anonymous in askapatient.com on August 6, 2012 @ 12:00 am

Side Effects: Foggy head, some dizziness, feeling intoxicated with no slurred speech. More irritability and feeling like I could fall asleep any time of day, interrupted concentration and word search...

Druginformer Identified Side Effects: Irritability

Posted By Anonymous in drugs.com on August 1, 2012 @ 12:00 am

This has been the only medicine to help with my insomnia and I've tried a lot. Unfortunately, I'm finding I'm also irritable most of the day since I've ramped up to 3 pills per day. I'm cutting bac...

Druginformer Identified Side Effects: Mood swings, Anxiety, Aggression, Depression, Irritability

Posted By Anonymous in askapatient.com on July 24, 2012 @ 12:00 am

Side Effects: woorsening of depression, anxiety, irratibility, aggression and wild mood swings. I don't believe it was worth the side effects for the little pain relief I got from the drug....

Druginformer Identified Side Effects: Gambling, Irritability, Somnolence, Personality change

Posted By Anonymous in askapatient.com on June 30, 2012 @ 12:00 am

Side Effects: Sleepiness, irritability, personality changes, gambling, lying This drug has turned someone I love very much into a raging gambling addict who goes to any means necessary to g...

Druginformer Identified Side Effects: Nausea, Irritability, Mood altered

Posted By Anonymous in drugs.com on April 23, 2012 @ 12:00 am

... me to sleep through the night. I wake up every morning in pain, which continues on and off all day. However, I have very little side effect (occasional sadness, irritability, nausea). Neurontin al...

Druginformer Identified Side Effects: Memory impairment, Diarrhoea, Irritability, Weight decreased

Posted By Anonymous in askapatient.com on April 5, 2011 @ 12:00 am

Can not do more than one task at a time. I forget EVERYTHING!!! Sometimes I think things are moving that my husband says aren't. I have had loose stool since I started the medicine. I ...

* Warning: The facts and figures contained in these reports are accurate to the best of our capability; however, our metrics are only meant to augment your medical knowledge, and should never be used as the sole basis for selecting a new medication. As with any medical decision, be sure to work with your doctor to ensure the best choices are made for your condition.

* About FAERS: The FDA Adverse Event Reporting System (FAERS) is used by FDA for activities such as looking for new safety concerns that might be related to a marketed product, evaluating a manufacturer's compliance to reporting regulations and responding to outside requests for information. Reporting of adverse events is a voluntary process, and not every report is sent to FDA and entered into FAERS. The FAERS database may contain duplicate reports, the report quality is variable, and many factors may influence reporting (e.g., media attention, length of time a drug is marketed, market share). For these reasons, FAERS case reports cannot be used to calculate incidence or estimates of risk for a particular product or compare risks between products.