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Naphazoline Hydrochloride; Pheniramine Maleate Related Rebound Effect

Official FDA Reports2
Social Media Events1
Active Ingredients
  • Naphazoline Hydrochloride; Pheniramine Maleate
Additional Terms for Rebound Effect
  • Rebound Outbreak

  This report is for all products sharing this active ingredient. For more details, please use our Workbench for research on individual brands like Opcon-a.


The quarterly trend chart illustrates changing levels of adverse events over time. Results from both the FDA Adverse Event Database (AERS) and adverse events extracted from social media by Druginformer are plotted side-by-side for easy comparison.

List of Possible Side Effects Reported

Report Date Dosage Indication Outcome Country Gender Age Weight (lbs)

* DrugInformer calculates alarm using a proprietary algorithm. Alarm should not be taken as an ofiicial signal from the FDA or other regulatory entity.

Social Media Comments From Around the Web

The following are comments from users that experienced side effects while taking Milnacipran Hydrochloride


Potential for rebound effects Cheap when purchased as 2+2, Gets The Red Out!, Soothes Tired Eyes An Insomniac's Morning Essential Red, bloodshot eyes are not the most fun thi...

Source:" Visine-A-C-Eye-Drops-review-8050

View full report on drug related rebound effect

Did the author experience rebound effect while taking visine-a?

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Tell us about your Experience with Naphazoline Hydrochloride; Pheniramine Maleate Related Rebound Effect

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Druginformer Identified Side Effects: Ocular hyperaemia, Rebound effect

Posted By LuvToShop11 in viewpoints.com

... the day. Since I always have red eyes when I wake up, I started using the Visine daily and I continue to do so. The packaging does say that overuse may cause more eye redness (rebound effects), but af...

* Warning: The facts and figures contained in these reports are accurate to the best of our capability; however, our metrics are only meant to augment your medical knowledge, and should never be used as the sole basis for selecting a new medication. As with any medical decision, be sure to work with your doctor to ensure the best choices are made for your condition.

* About FAERS: The FDA Adverse Event Reporting System (FAERS) is used by FDA for activities such as looking for new safety concerns that might be related to a marketed product, evaluating a manufacturer's compliance to reporting regulations and responding to outside requests for information. Reporting of adverse events is a voluntary process, and not every report is sent to FDA and entered into FAERS. The FAERS database may contain duplicate reports, the report quality is variable, and many factors may influence reporting (e.g., media attention, length of time a drug is marketed, market share). For these reasons, FAERS case reports cannot be used to calculate incidence or estimates of risk for a particular product or compare risks between products.